Ca1 - OmicsDI

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Transcription profiling by array (72)
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Lab affiliation

Department of Animal and Poultry Sciences and the School of Neuroscience, Virginia Tech, Blacksburg, VA, USA (10)
Department of Translational Research in Psychiatry Max Planck Institute of Psychiatry, Munich (2)
1. CERVO Brain Research Centre, Quebec Mental Health Institute; Québec, QC, G1E 1T2, Canada. 2. Department of Psychiatry & Neuroscience, Université Laval; Québec, QC, G1V 0A6, Canada. (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Associate Professor, School of Animal Sciences Core Faculty, School of Neuroscience Faculty of Health Sciences Vice Chair, Institutional Biosafety Committee (IBC) Virginia Tech (1)
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Cognitive Disorder Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (1)
Department for Neurology Section Translational Neuroimmunology Jena University Hospital Am Klinikum 1, D-07747 Jena, Germany (1)
Department of Biomedical Engineering, Lund University, Lund, Sweden (1)
Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS). India. (1)
Department of Fundamental Neurosciences, University of Lausanne, Switzerland (1)
Department of Medical Mycology, Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College (1)
Department of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College (1)
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, The Netherlands (1)
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, The Netherlands (1)
Department of Neurosciences, University of Toledo (1)
Department of Neurosurgery, Neurosurgical Research Institute, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China (1)
Department of Pharmacology University of North Carolina (1)
Dept. of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, The Netherlands (1)
Direktor Institut für Neuroanatomie und Zellbiologie Medizinische Hochschule Hannover (MHH) (1)
Division of Radiation Health, Department of Pharmaceutical Sciences, Neurobiology & Developmental Sciences, University of Arkansas for Medical Sciences (1)
ETH Zürich D-HEST Institut für Neurowissenschaften Molecular and Behavioral Neuroscience (1)
Group Leader, Quattrocolo Lab, Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology (NTNU), Trondheim 7491, Norway (1)
Huazhong University of Science and Technology, China (1)
IRCCS Istituto G Gaslini (1)

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pathogen:virus (1)
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The Influence of Sleep Deprivation on Hippocampal CA1 Gene Expression: Relation to Stress and Aging

Sleep deprivation (SD) in young adults is associated with metabolic, stress and cognitive responses that are also characteristic of brain aging. Given that sleep architecture changes with age, including increased fragmentation and decreased slow wave activity, it seems reasonable to investigate pote...

ORGANISM(S): Rattus norvegicus

2012-07-16 | E-GEOD-34424 | biostudies-arrayexpress

Transcription profiling by array of hippocampal regions CA1, CA3, and DG from aged, calorically restricted rats

Aging is associated with a decline in hippocampal mediated learning and memory, a process which can be ameliorated by dietary (caloric) restriction. We used Affymetrix gene expression analysis to monitor changes in three regions of the hippocampus (CA1, CA3, DG) of middle aged (18 months) and old (2...

ORGANISM(S): Rattus norvegicus

2010-06-08 | E-GEOD-21681 | biostudies-arrayexpress

Transcriptional profiling of Rattus norvegicus brain hippocampal CA1 regions after kainic acid induced status epilepticus and untreated controls.

In this study we used microarray analysis to reveal the gene expression profile of the hippocampal CA1 subregion, which was laser-capture microdissected one week after kainic acid (KA)-induced status epilepticus (SE) in postnatal day 21 (P21) rats. These rats are developmentally roughly comparable t...

ORGANISM(S): Rattus norvegicus

2010-10-25 | E-TABM-881 | biostudies-arrayexpress

Zbtb20-mediated repression of genes in developing CA1 pyramidal neurons

The transcriptional repressor Zbtb20 is essential for specification of hippocampal CA1 pyramidal neurons. Moreover, ectopic expression of Zbtb20 is sufficient to transform subicular and retrosplenial areas of D6/Zbtb20S mice to CA1. We used microarrays to identify genes that are repressed by Zbtb20 ...

ORGANISM(S): Mus musculus

2014-04-11 | E-GEOD-38837 | biostudies-arrayexpress

Transcription profiling of rat hippocampus from young and aged rats with age-related spatial learning impairments

The aim of this study was to investigate whether the differences in memory decline associated with aging are a result of differences in gene expression. We first categorized age-unimpaired and age-impaired rats based on their performance in the Morris Water Maze and then isolated messenger RNA from...

ORGANISM(S): Rattus norvegicus

2007-11-06 | E-GEOD-3531 | biostudies-arrayexpress

Transcription profiling of rat hippocampus CA1 and CA3 areas response to oxidative stress

Mechanistic study on the differential responses of the two hippocampal adjoining regions, i.e., CA1 and CA3, to elevated oxidative stress. Experiment Overall Design: Time course study. Involved four time points and comparison of two brain regions.

ORGANISM(S): Rattus norvegicus

2008-06-15 | E-GEOD-6693 | biostudies-arrayexpress

Calorie restriction suppresses age-dependent hippocampal transcriptional signatures.

Calorie restriction (CR) enhances longevity and mitigates aging phenotypes in numerous species. Physiological responses to CR are cell-type specific and variable throughout the lifespan; however, the mosaic of molecular changes responsible CR benefits remain unclear, particularly in brain regions su...

ORGANISM(S): Mus musculus

2015-07-14 | E-GEOD-69952 | biostudies-arrayexpress

Transcription profile of aging and cognitive-related genes in the medial prefrontal cortex and hippocampal region CA1

This study focused on transcription in the medial PFC (mPFC) as a function of age and cognition. Young and aged F344 rats were characterized on tasks, attentional set shift and spatial memory, which depend on the mPFC and hippocampus, respectively. Differences in transcription associated with age an...

ORGANISM(S): Rattus norvegicus

2016-05-17 | E-GEOD-75772 | biostudies-arrayexpress

Functionally diverse dendritic mRNAs rapidly associate with ribosomes following a novel experience

The subcellular localization and translation of messenger RNA (mRNA) supports functional differentiation between cellular compartments. In neuronal dendrites, local translation of mRNA provides a rapid and specific mechanism for synaptic plasticity and memory formation, and might be involved in the ...

ORGANISM(S): Mus musculus

2014-07-30 | E-GEOD-58343 | biostudies-arrayexpress

Transcriptome Profiling of Hippocampal CA1 After Early Life Seizure-Induced Preconditioning May Elucidate New Genetic Therapies for Epilepsy

Injury of the CA1 subregion induced by a single injection of kainic acid (1M-CM-^WKA) is attenuated when juvenile animals (P20) have a history of two sustained neonatal seizures on P6 and P9. To identify gene candidates involved in the spatially protective effects produced by early life conditioning...

ORGANISM(S): Rattus norvegicus

2013-02-14 | E-GEOD-44031 | biostudies-arrayexpress

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