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ProteomicsCab45-dependent facilitation of insulin secretory granule biogenesis and its dysregulation in type 2 diabetes
Germanos M1*. Yau B1*. Taper M1. An Y1. Yeoman C1. Wilson A1. Cattin-Ortolá J2. Maslar D3. Tong J1. Naghiloo S1. Needham E4. Diaz-Vegas A4. Larance M1. Thomas H5. Seidah NG6. von Blume J7. James DE4. Thorn P1. Ailion M2. Asensio C3. Kebede MA1. 1 School of Medical Sciences, Charles Perkins Centre, ...
ORGANISM(S): Rattus rattus (Black rat) 
2024-12-02 | PXD052042 | Pride
Islet Cab45 Insulin 
UnknownFam20C regulates protein secretion by Cab45 phosphorylation.
Not available
S-EPMC7265331 | biostudies-literature
UnknownSecretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network.
Not available
S-EPMC4862333 | biostudies-literature
UnknownCab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning.
Not available
S-EPMC9825660 | biostudies-literature
UnknownCalcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells.
Not available
S-EPMC10398874 | biostudies-literature
UnknownActivity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network.
Not available
S-EPMC6261503 | biostudies-literature
UnknownER export via SURF4 uses diverse mechanisms of both client and coat engagement.
Not available
S-EPMC11557686 | biostudies-literature
UnknownCalcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells.
Not available
S-EPMC8379914 | biostudies-literature
UnknownMayday sustains trans-synaptic BMP signaling required for synaptic maintenance with age.
Not available
S-EPMC7935490 | biostudies-literature
UnknownPSKH1 kinase activity is differentially modulated via allosteric binding of Ca<sup>2+</sup> sensor proteins.
Not available
S-EPMC11873932 | biostudies-literature
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