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TranscriptomicsWhole genome gene expression profiling in CD4+ T-cells, FACS-sorted based on CADM1/CD7 expression levels, in Adult T-cell Leukemia-lymphoma (ATL) patients, HTLV-1 carriers, and in healthy volunteers.
CADM1 overexpresion and stepwise downregulation of CD7 in CD4+T-cells from ATL patients and HTLV-1 carriers accurately reflect the process of disease, i.e., oligoclonally and clonally exanding cells are accumulated in D (CADM1posCD7dim) and N (CADM1posCD7neg) populations, respectively. Moreover, gen...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-55851 | biostudies-arrayexpress
GenomicsCADM1-overexpression ES-2 cells
CADM1-overexpression ES-2 cells
PRJNA589830 | ENA
GenomicsEffects of CADM1 expression in human melanoma
Effects of CADM1 expression in human melanoma
PRJNA529484 | ENA
TranscriptomicsCADM1-overexpression ES-2 cells
CADM1, an immunoglobulin superfamily member, frequently inactivated but function as a tumor suppressor in many solid tumors. However, how CADM1 expression in ovarian cancer cells and the mechanisms of its tumor suppressor function is not fully understood. We created ovarian cancer ES-2 cell lines in...
ORGANISM(S): Homo sapiens 
2019-11-16 | GSE140453 | GEO
TranscriptomicsEffects of CADM1 expression in human melanoma
CADM1 expression in non-adherent conditions was found to potently induce caspase-independent cell death. We sought to use microarray analysis to glean insights to the mechanism associated with CADM1 induced non-adherent cell death.
ORGANISM(S): Homo sapiens 
2019-04-03 | GSE128954 | GEO
GenomicsMyeloid Cell Adhesion Molecule 1 (CADM1) promotes pro-inflammatory signaling during Inflammatory Bowel Disease.
Myeloid Cell Adhesion Molecule 1 (CADM1) promotes pro-inflammatory signaling during Inflammatory Bowel Disease.
PRJNA1139190 | ENA
ProteomicsPIEZO1 Interactome in HEK cells
The propeller-shaped blades of the PIEZO1 and PIEZO2 ion channels partition into the plasma membrane and respond to indentation or stretching of the lipid bilayer, thus converting mechanical forces into signals that can be interpreted by cells, in the form of calcium flux and changes in membrane pot...
ORGANISM(S): Homo sapiens (Human) 
2024-10-30 | PXD054618 | Pride
Cadm1 Piezo1 Mechanosensation Ion channel 
GenomicsMyeloid Cell Adhesion Molecule 1 (CADM1) promotes pro-inflammatory signaling in human Inflammatory Bowel Diseases
Myeloid Cell Adhesion Molecule 1 (CADM1) promotes pro-inflammatory signaling in human Inflammatory Bowel Diseases
PRJNA1302204 | ENA
UnknownCADM1 associates with Hippo pathway core kinases; membranous co-expression of CADM1 and LATS2 in lung tumors predicts good prognosis.
Not available
S-EPMC6609799 | biostudies-literature
GenomicsIdentification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
PRJNA1363778 | ENA
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