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TranscriptomicsPOU4F1 is associated with t(8;21) AML and contributes directly to its unique transcriptional signature
POU4F1 is associated with t(8;21) acute myeloid leukemia (AML) and contributes directly to its unique transcriptional signature To identify targets of POU4F1, we performed gene expression profiling, comparing Pou4f1+/+ or Pou4f1-/- fetal liver cells to cells overexpressing POU4F1 and identified 140 ...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-19997 | biostudies-arrayexpress
TranscriptomicsThe impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells
The extent to which differences in germ line DNA copy number contribute to natural phenotypic variation is unknown. We analyzed the copy number content of the mouse genome to a sub-10 kb resolution. We identified over 1,300 copy number variant regions (CNVRs), most of which are < 10 kb in length, ar...
ORGANISM(S): Mus musculus 
2009-03-08 | E-GEOD-10656 | biostudies-arrayexpress
TranscriptomicsDonor cell type influences the epigenome and differentiation potential of human induced pluripotent stem cells
This SuperSeries is composed of the following subset Series: GSE27134: DNA methylation data from human iPS cells, ES cells, cord blood, and keratinocytes GSE27186: Expression data of human somatic cell types and induced pluripotent stem cells GSE31742: DNA methylation data from human keratinocyte-de...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-27224 | biostudies-arrayexpress
TranscriptomicsDissecting engineered cell types and enhancing cell fate conversion via CellNet
Engineering clinically relevant cells in vitro holds promise for regenerative medicine, but most protocols fail to faithfully recapitulate target cell properties. To address this, we developed CellNet, a network biology platform that determines whether engineered cells are equivalent to their target...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-59037 | biostudies-arrayexpress
UnknownCell cycle expression heterogeneity predicts degree of differentiation.
Not available
S-EPMC11291076 | biostudies-literature
UnknownIntegrated genomics of susceptibility to alkylator-induced leukemia in mice.
Not available
S-EPMC3018144 | biostudies-literature
UnknownSingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species.
Not available
S-EPMC6715530 | biostudies-literature
UnknownCell cycle expression heterogeneity predicts degree of differentiation.
Not available
S-EPMC11500603 | biostudies-literature
UnknownOneSC: a computational platform for recapitulating cell state transitions.
Not available
S-EPMC11630913 | biostudies-literature
UnknownOneSC: A computational platform for recapitulating cell state transitions.
Not available
S-EPMC11185539 | biostudies-literature
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