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The ability to correlate chromosome conformation and gene expression gives a great deal of information regarding the strategies used by a cell to properly regulate gene activity. 4C-seq is a relatively new and increasingly popular technology where the set of genomic interactions generated by a singl...
ORGANISM(S): Mus musculus 
The spatial proximity between regulatory elements and their target genes has a profound affect on gene expression. X Chromosome Inactivation (XCI) is an epigenetic process by which an entire chromosome is rendered, for the most part, transcriptionally silent. A few genes are known to escape XCI and ...
ORGANISM(S): Mus musculus 
We present HDX-MS data of the BAM:SurA complex to define the interaction sites for SurA on BAM and vice versa.
ORGANISM(S): Escherichia coli 
2022-07-12 | PXD030268 | Pride
Here, we have used a SARS-naïve, bovine ultralong CDRH3 library to isolate a bovine paratope that engages the SARS-CoV and SARS-CoV-2 receptor-binding domain (RBD). This scFv (B9-scFv) neutralises viruses pseudo-typed with SARS-CoV Spike protein. Using differential hydrogen-deuterium exchange mass s...
ORGANISM(S): Bos taurus (Bovine) 
2023-03-11 | PXD032965 | Pride
Here we present HDX-MS data to study the conformational dynamics of BAM, BAM(T434A) and BAM(LVPR).
ORGANISM(S): Escherichia coli 
2025-10-13 | PXD057055 | Pride
This Series reports data from a CTCF ChIP-Seq experiment performed in F1-hybrid mouse trophoblast stem cells (TSCs). The data are part of a larger study examining inactive X gene expression and chromatin states, reported as GEO Series GSE39406. Included for this dataset are FASTQ files, BED alignmen...
ORGANISM(S): Mus musculus 
Mice lacking p53 and one or two alleles of the cyclin D-dependent kinase inhibitor p18Ink4c are prone to medulloblastoma development. The tumor frequency is increased by exposing postnatal animals to ionizing radiation at a time when their cerebella are developing. In irradiated mice engineered to e...
ORGANISM(S): Mus musculus 
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