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Calcium-activated potassium channels are important membrane proteins that help in maintaining the cellular physiology and cell signalling. Till date no Calcium-activated potassium channels have been identified in Leishmania donovani. It’s gene was cloned into pET vector and expressed in E. coli BL21...
ORGANISM(S): Leishmania sp. MHOM/IN/80/DD8 Leishmania donovani 
2021-05-11 | PXD019577 | Pride
Background: Ion channels are key determinants for the function of excitable cells but little is known about their role and involvement during cardiac development. Earlier work identified Ca2+-activated potassium channels of small and intermediate conductance (SKCas) as important regulators of neural...
ORGANISM(S): Mus musculus 
Targeting the calcium-activated K+ channel KCa3.1 in pancreatic ductal adenocarcinoma
The MaxiK potassium channel is a key modulator of smooth muscle tone. Due to its calcium and voltage sensitivity, MaxiK is activated following depolarization and Ca2+ mobilization, therefore relaxing the muscle. We investigate the effects of silencing MaxiK for 48h in corpus cavernosuml smooth muscl...
ORGANISM(S): Homo sapiens 
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