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TranscriptomicsA novel 3-D organotypic culture model by co-culturing alpha-SMA positive CAF and cholangiocarcinoma cells in a collagen matrix
The increased M-NM-1-smooth muscle-actin positive cancer-associated fibroblastic cells (CAF) in the desmoplastic stroma may relate to a more aggressive cancer and worse survival outcomes for intrahepatic cholangiocarcinoma (ICC) patients We developed a novel 3-D organotypic culture model by co-cultu...
ORGANISM(S): Rattus norvegicus 
2012-06-22 | E-GEOD-38889 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas
Characterization of preclinical models of intrahepatic cholangiocarcinoma progression that reliably recapitulate altered molecular features of the human disease. Here, we performed comprehensive gene expression profiling of cholangiocarcinoma tumors arising from bile duct inoculation of different gr...
ORGANISM(S): Rattus norvegicus 
2012-06-20 | E-GEOD-38834 | biostudies-arrayexpress
UnknownGlobal burden of Clostridium difficile infections: a systematic review and meta-analysis.
Not available
S-EPMC6304170 | biostudies-literature
UnknownActivation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.
Not available
S-EPMC9664095 | biostudies-literature
UnknownRandomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer.
Not available
S-EPMC5321098 | biostudies-literature
UnknownGlobal and regional estimates of the morbidity due to type I diabetes among children aged 0-4 years: a systematic review and analysis.
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S-EPMC6214490 | biostudies-literature
UnknownSex Differences in Cardiac Troponin I and T and the Prediction of Cardiovascular Events in the General Population.
Not available
S-EPMC8486023 | biostudies-literature
UnknownPhase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050)☆.
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S-EPMC8477142 | biostudies-literature
UnknownGenetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder.
Not available
S-EPMC2678909 | biostudies-literature
UnknownA Systematic Review and Meta-Analysis on Effects of Bicarbonate Therapy on Kidney Outcomes.
Not available
S-EPMC7938083 | biostudies-literature
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