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ProteomicsMulit-omics analysis of keratinocytes reveals dermokine as regulator keratinocyte differentiation and adhesion - phosphoproteome and proteome
Impaired adhesion and differentiation of keratinocytes is a hallmark of several skin diseases, but only some of the factors that regulate these processes have been identified. Here, we studied the role of isoform-rich dermokine – a wound- and tumor-regulated protein – in keratinocytes using a combin...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD050151 | Pride
ProteomicsMulit-omics analysis of keratinocytes reveals dermokine as regulator keratinocyte differentiation and adhesion - p120 perturbed proteome
Impaired adhesion and differentiation of keratinocytes is a hallmark of several skin diseases, but only some of the factors that regulate these processes have been identified. Here, we studied the role of isoform-rich dermokine – a wound- and tumor-regulated protein – in keratinocytes using a combin...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD074943 | Pride
UnknownThe predictive performance of SAPS 2 and SAPS 3 in an intermediate care unit for internal medicine at a German university transplant center; A retrospective analysis.
Not available
S-EPMC6760764 | biostudies-literature
ProteomicsMulit-omics analysis of keratinocytes reveals dermokine as regulator keratinocyte differentiation and adhesion - 3D Proteome
Impaired adhesion and differentiation of keratinocytes is a hallmark of several skin diseases, but only some of the factors that regulate these processes have been identified. Here, we studied the role of isoform-rich dermokine – a wound- and tumor-regulated protein – in keratinocytes using a combin...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD055812 | Pride
UnknownWhy Bile Acids Are So Important in Non-Alcoholic Fatty Liver Disease (NAFLD) Progression.
Not available
S-EPMC6912605 | biostudies-literature
ProteomicsPathological meprin a activity associated with degradation of dermokine drives a psoriasis-like skin phenotype in a novel genetic mouse model
Keratinocyte proliferation and differentiation is regulated via proteolytic networks. Dysregulation of proteases within these systems can cause hyperproliferative and inflammatory skin disorders. In healthy skin the metalloprotease meprin α is localized in the stratum basale, yet in wound healing ti...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-03 | PXD063928 | Pride
Degradomics Dia Mouse Psoriasis Tails Dermokine 
UnknownImplications of Immunotherapy in Hepatobiliary Tumors.
Not available
S-EPMC6597927 | biostudies-literature
UnknownA non-interventional study of the genetic polymorphisms of NOD2 associated with increased mortality in non-alcoholic liver transplant patients.
Not available
S-EPMC3890629 | biostudies-literature
UnknownLiver failure-future challenges and remaining questions.
Not available
S-EPMC8106069 | biostudies-literature
ProteomicsInstaNovo-P: A de novo peptide sequencing model for phosphoproteomics
Phosphorylation, a crucial post-translational modification (PTM), plays a central role in cellular signaling and disease mechanisms. Mass spectrometry-based phosphoproteomics is widely used for system-wide characterization of phosphorylation events. However, traditional methods struggle with accurat...
ORGANISM(S): Homo sapiens (Human) 
2026-05-20 | PXD074105 | Pride
Instanovo  de novo sequencing  phosphoproteomics  breast cancer  fgfr2 signaling 
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