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we engineered a β-glucan (Dex)-stabilized mulberry leaf lipid-based nanovaccine (DPML@OVA-CpG) that protected vaccine components during GI transit and facilitated their specific delivery to the GALTs. Following oral administration, the DPML@OVA-CpG underwent M cell-mediated transcytosis in the small...
2026-08-25 | MTBLS15453 | MetaboLights
We used a streamlined pipeline for the generation of personalized cancer vaccines starting from the isolation and selection of the most immunogenic peptide candidates expressed on the tumour cells and ending in the generation of efficient therapeutic oncolytic cancer vaccines. We used MHC-I immunoaf...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-06 | PXD026463 | Pride
Personalized Breast Cancer Vaccines Based on Genome Sequencing
Personalized Breast Cancer Vaccines Based on Genome Sequencing
Proteomic analysis for In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
ORGANISM(S): Mus Musculus 
2022-07-14 | PXD035315 |
Personal Neoantigen Cancer Vaccines
Dendritic cell (DC) vaccines have been proposed as cancer immunotherapies due to their role as crucial antigen-presenting cells that regulate T cell functions. Despite considerable efforts to optimize ex vivo priming of DCs, DC vaccines have rarely been successful, suggesting the presence of unknown...
2025-11-03 | MTBLS10389 | MetaboLights
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