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TranscriptomicsGene expression profiling of RPMI-grown and macrophage-internalized Candida glabrata wild-type, Cgrsc3-aM-bM-^HM-^F and Cgrtt109M-bM-^HM-^F cells.
To delineate the interaction of Candida glabrata with host immune cells, we performed genome-wide transcriptional profiling analysis on THP-1 macrophage-internalized wild-type and chromatin remodeling defective mutant (Cgrsc3-aM-bM-^HM-^F and Cgrtt109M-bM-^HM-^F) yeasts. Genes implicated in ergos...
ORGANISM(S): Candida glabrata 
2012-08-18 | E-GEOD-38953 | biostudies-arrayexpress
TranscriptomicsTranscriptional Response of Candida albicans Cells Following Phagocytosis by Mouse Macrophages
Transcriptional profiling of Candida albicans that had been phagocytosed for 1, 2, or 4 hours by either bone marrow-derived mouse macrophaged (BMDM) or immortalized RAW264.7 cells Keywords: Time course Two-condition experiment, phagocytosed cells vs cells maintained in D-10 media. Time course: 1, 2,...
ORGANISM(S): Candida albicans 
2008-07-28 | E-GEOD-11399 | biostudies-arrayexpress
TranscriptomicsMicroevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant
Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of drug resistance. Here we used an experimental...
ORGANISM(S): Candida albicans 
2015-03-31 | E-GEOD-56174 | biostudies-arrayexpress
UnknownFunctional genomic analysis of Candida glabrata-macrophage interaction: role of chromatin remodeling in virulence.
Not available
S-EPMC3420920 | biostudies-literature
ProteomicsExtracellular Vesicles (EVs) fromTHP1 macrophages upon C.albicans interaction
TMT isotopic labelling to relative Quantitation of proteins from THP1 Macrophage EVs after C.albicans interaction.
ORGANISM(S): Bos taurus (Bovine) Candida albicans (Yeast) Homo sapiens (Human) 
2022-02-28 | PXD004517 | Pride
Evs Candida-macrophage interaction Tmt 
TranscriptomicsGene expression profiling of RPMI-grown and macrophage-internalized Candida glabrata wild-type, Cgrsc3-a∆ and Cgrtt109∆ cells.
To delineate the interaction of Candida glabrata with host immune cells, we performed genome-wide transcriptional profiling analysis on THP-1 macrophage-internalized wild-type and chromatin remodeling defective mutant (Cgrsc3-a∆ and Cgrtt109∆) yeasts. Genes implicated in ergosterol biosynthesis, and...
ORGANISM(S): Nakaseomyces glabratus Nakaseomyces glabratus CBS 138 
2012-08-18 | GSE38953 | GEO
UnknownPhagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis.
Not available
S-EPMC5278172 | biostudies-literature
UnknownDectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments.
Not available
S-EPMC556398 | biostudies-literature
UnknownRab14 regulates maturation of macrophage phagosomes containing the fungal pathogen Candida albicans and outcome of the host-pathogen interaction.
Not available
S-EPMC4363425 | biostudies-literature
UnknownTemporal transcriptional response of Candida glabrata during macrophage infection reveals a multifaceted transcriptional regulator CgXbp1 important for macrophage response and fluconazole resistance.
Not available
S-EPMC11554308 | biostudies-literature
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