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UnknownIdentification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity.
Not available
S-EPMC4060222 | biostudies-literature
UnknownBilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance.
Not available
S-EPMC8498001 | biostudies-literature
UnknownInhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells.
Not available
S-EPMC10950707 | biostudies-literature
UnknownDisruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass.
Not available
S-EPMC6290731 | biostudies-literature
TranscriptomicsTranscription profiling by array of human pacreatic islets prepared for clinical transplantation
This study compared 9 human islet preparations, extracted and prepared for clinical transplantation. Human islets were isolated as, and all were of transplant quality. Unamplified RNA was extracted and hybridized to Affymetrix HGU133+2 arrays. By using gene set enrichment analysis to investigate the...
ORGANISM(S): Homo sapiens 
2011-02-26 | E-MTAB-203 | biostudies-arrayexpress
ProteomicsPSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins
Protein Serine Kinase H1 (PSKH1) was recently identified as a crucial factor in kidney development and is overexpressed in prostate, lung and kidney cancers. However, little is known about PSKH1’s regulation, leading to its classification as a “dark” kinase. Here, we used biochemistry and mass spect...
ORGANISM(S): Homo sapiens (Human) 
2025-01-26 | PXD056543 | Pride
Protein kinase  allosteric regulation  calumenin  erc-55  cab-45 
ProteomicsPSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins
Protein Serine Kinase H1 (PSKH1) was recently identified as a crucial factor in kidney development and is overexpressed in prostate, lung and kidney cancers. However, little is known about PSKH1’s regulation, leading to its classification as a “dark” kinase. Here, we used biochemistry and mass spect...
ORGANISM(S): Homo sapiens (Human) 
2025-01-26 | PXD058954 | Pride
Calcium Ionomycin Pskh1 
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