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ProteomicsSphingosine kinase 2 deficiency impairs VLDL secretion by inhibiting mTORC2 phosphorylation and activating chaperone-mediated autophagy
Hepatic very low-density lipoprotein (VLDL) is essential for maintaining lipid metabolism in the liver. Sphingosine kinases (SphKs) are essential rate-limiting enzymes that catalyze sphingosine phosphorylation to Sphingosine-1-phosphate (S1P). SphKs exist as two isoforms, SphK1 and SphK2, both highl...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-13 | PXD059594 | Pride
Sphk2 Cma Vldl Mtorc2 
ProteomicsLysine methylation in cyanobacteria
Deciphering structure, function and mechanism of a new lysine methyltransferase cKMT1 in model cyanobacterium Synechocystis sp. PCC 6803
ORGANISM(S): Synechocystis Sp. Pcc 6803 
2022-07-29 | PXD035617 |
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