Sort   by:  
 Page size 
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
TranscriptomicsImproved transcription and translation with L-leucine stimulation of mTORC1
Roberts syndrome (RBS) is a human developmental disorder caused by mutations in the cohesin acetyltransferase ESCO2. We previously reported that mTORC1 was inhibited and overall translation was reduced in RBS cells. Treatment of RBS cells with L-leucine partially rescued mTOR function and protein sy...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-64962 | biostudies-arrayexpress
TranscriptomicsMitochondrial functional aberrations in a mouse model of non-ischemic heart failure
We characterized the metabolic and cardiac mitochondrial function in a mouse model of non-ischemic HF. Inhibition of nitric oxide synthesis and hypertension, which often present together, are two important risk factors in human non-ischemic HF. Compared with L-NAME L-NG-Nitroarginine methyl ester (L...
ORGANISM(S): Mus musculus 
2016-01-19 | E-GEOD-72132 | biostudies-arrayexpress
TranscriptomicsEthylene and 1-MCP differentially regulate gene expression during onion (Allium cepa L.) sprout suppression
Onion is regarded as non-climacteric. In onion, ethylene can suppress sprouting however, the ethylene binding inhibitor, 1-MCP can also suppress sprout growth although it is unknown how ethylene and 1-MCP elicit the same response. In this study, onion bulbs were treated with 10 μL L-1 ethylene or 1...
ORGANISM(S): Allium cepa 
2011-06-29 | E-GEOD-27132 | biostudies-arrayexpress
ProteomicsIntegrative genomic and proteomic analysis of response of Lactobacillus casei str. Zhang to glucose limitation
Nutrient starvation is an important survival challenge for bacteria during industrial production of functional foods. Lactobacilli are increasingly being used as probiotics in functional foods. As next-generation sequencing technology has greatly advanced, we performed integrative proteomic and geno...
ORGANISM(S): Lactobacillus casei str. Zhang 
2018-02-08 | PXD006643 | Pride
Lactobacillus casei str. zhang  lace of glucose 
TranscriptomicsTranscription profiling of raspberry buds in a time series during dormancy release
Co-ordinated gene expression during phases of dormancy release in raspberry (Rubus idaeus L.) buds
ORGANISM(S): Rubus idaeus 
2007-02-02 | E-MEXP-825 | biostudies-arrayexpress
UnknownBiomarkers of the L-Arginine/Dimethylarginine/Nitric Oxide Pathway in People with Chronic Airflow Obstruction and Obstructive Sleep Apnoea.
Not available
S-EPMC10455103 | biostudies-literature
TranscriptomicsDegradome sequencing reveals endogenous small RNA targets in rice (Oryza sativa L. ssp. indica)
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) regulate gene expression in eukaryotes. Plant miRNAs modulate their targets mainly via messenger RNA (mRNA) cleavage. Small RNA targets have been extensively investigated in Arabidopsis using computational prediction, experimental validation, an...
ORGANISM(S): Oryza sativa Indica Group 
2010-01-01 | E-GEOD-19050 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of jejunum from chickens with either a high or low natural antibody response which were fed an organic or conventially produced diet
ISA Brown Warren medium heavy layer hens were divergently selected for 25 generations on their primary immune response. Two selection chicken lines were established: chickens with a high natural antibody response (H) and chicken with a low natural antibody response (L). Besides a control line of ran...
ORGANISM(S): Gallus gallus 
2010-03-02 | E-MEXP-1798 | biostudies-arrayexpress
GenomicsWhole genome sequencing of spontaneous resistant mutants of Mycobacterium tuberculosis H37Rv selectec in the presence of BVL3572S and amino acids
M. tuberculosis H37Rv cultures were exposed to BVL3572S in the absence or presence of L-histidine or L-alanine for at least 4 weeks. Individual colonies were picked and their genomic DNA extracted, indexed, and sequenced.
ORGANISM(S): Mycobacterium tuberculosis 
2026-06-03 | E-MTAB-17255 | biostudies-arrayexpress
Sort   by:  
 Page size