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ProteomicsProteomic profiling reveals age-dependent remodeling of backfat and key regulatory proteins linked to carcass traits in ningxiang pigs
Adipose tissue plays a critical role in growth, energy metabolism, and carcass composition in pigs. However, the age-dependent molecular mechanisms underlying backfat development remain poorly characterized, particularly in native breeds such as the Ningxiang pig, which exhibits high fat deposition ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-06-08 | PXD067020 | Pride
Backfat development Carcass traits Adipose tissue Lipid metabolism. Proteomics 
TranscriptomicsChIP-chip from H9 hESCs for RNA Polymerase II, TBP, TAF3, TAF5, TAF7, and TAF11
The general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and approximately 14 TBP-associated factors (TAFs). Here we find, unexpectedly, that undifferentiated human embryonic stem cells (hESCs) contain only six TAFs (TAFs 2, 3, 5, 6, 7 and 11), whereas following diffe...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-39312 | biostudies-arrayexpress
ProteomicsHuman Neutrophils in Pulmonary Arterial Hypertension by LC-MSMS
Neutrophil elastase (NE) is implicated in pulmonary arterial hypertension (PAH) but the role of neutrophils in the pathogenesis of PAH is unclear. Here we show that neutrophils from PAH vs. control subjects produce and release increased NE associated with enhanced extracellular trap formation. PAH n...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD023134 | Pride
Lc-msms Pulmonary arterial hypertension Neutrophils 
GenomicsJmjd3-mediated H3K27me3 dynamics orchestrate brown fat cell fate transition and regulate white fat plasticity
We performed ChIP-seq to chart genome-wide maps of H3K27me3 in brown preadipocytes and mature brown adipocytes. We observed a subset of brown fat-specific genes, but not common fat genes or white fat-specific genes, possess the H3K27me3 mark in preadipocytes, and this mark is erased in mature adipoc...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-55469 | biostudies-arrayexpress
TranscriptomicsJmjd3-mediated H3K27me3 dynamics orchestrate brown fat cell fate transition and regulate white fat plasticity (RNA-Seq)
We performed RNA-Seq for brwon fat, epididymal white fat and soleus muscle of mice to identify brown fat-selective, white fat-selective and common fat genes. RNA-Seq for brown fat, white fat and soleus muscle of wild type C56BL6 mice.
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-56367 | biostudies-arrayexpress
UnknownPredictive value of 8-year blood pressure measures in intracerebral haemorrhage risk over 5 years.
Not available
S-EPMC7616516 | biostudies-literature
ProteomicsThe influence of different Matrigel dissolving methods on proteome research of human derived organoids
Here we investigated the influence of different Matrigel dissolving methods on organoid proteomics.
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-10-12 | PXD029173 |
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