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TranscriptomicsGlobal analysis of metastasis-associated gene expression in the primary cultures from clinical specimens of ccRCC
Metastatic clear cell renal cell carcinoma (ccRCC) has a poor prognosis and unpredictable course and there are no molecular markers that reliably predict ccRCC metastasis. In this study, specimens from 84 patients with ccRCC were directly cultured in vitro. The primary cultures from 38 of 94 specime...
ORGANISM(S): Homo sapiens 
2008-08-27 | E-GEOD-11072 | biostudies-arrayexpress
ProteomicsSerum Metabolomics in Patients with Ocular Diseases
Serum metabolomics in patients with ocular diseases is a fascinating and emerging field of study. It involves analyzing the metabolites in blood serum to understand the biochemical processes and pathways associated with various eye conditions. This approach provides a deeper insight into the pathoph...
ORGANISM(S): Homo Sapiens 
2024-01-24 | PXD048826 |
Proteomicsproteins identified in biological activated carbon (BAC) filter
To obtain further insights into the role of bacterial activity in BAC filter performance, the expressed proteins of the bacterial community residing in the BAC filter were identified by a metaproteomic approach.
ORGANISM(S): environmental samples <Acidobacteria> environmental samples <Planctomycetacia> 
2022-10-13 | PXD015811 | Pride
Proteins Bac filter 
TranscriptomicsThe identification of genes related to METTL14 overexpression in radiation-induced hepatocyte death based on bioinformatics analysis
C57BL/6J mice were subjected to 30 Gy liver irradiation (5 Gy × 6 fractions). METTL14 overexpression was achieved via AAV-METTL14 tail-vein injection. Liver tissues were collected for RNA-seq analysis to identify differentially expressed genes (DEGs) related to cell death pathways.
ORGANISM(S): Mus musculus 
2026-05-04 | E-MTAB-16163 | biostudies-arrayexpress
TranscriptomicsActivation of autophagy by starvation and mTOR inhibition in three human cell lines
The aim of the project was to characterize changes in gene expression that are associated with induced autophagic flux. We engineered HeLa, HEK 293 and SH-SY5Y cell lines to express tandem-fluorecent LC3 (tf-LC3). The ratio of the red and green fluorophores indicated how much of the LC3 is in the ac...
ORGANISM(S): Homo sapiens 
2022-08-25 | E-MTAB-12020 | biostudies-arrayexpress
ProteomicsRBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma
Transient overexpress RBIS and control plasmid in H293T cells and collect cells after 48 hours, then performed IP assays using anti-Flag beads subjected samples to LC-MSMS to screen proteins interacting with RBIS.
ORGANISM(S): Homo Sapiens 
PXD057090 |
ProteomicsProteome and phosphoproteome landscape of silicosis occurrence in mice model
To map the multi-omics atlas of silicosis progression, we collected four replicates of whole lung lobes from mice at different stages (W2, W4, W6, W10) after silica-treated as well as W6 after PBS-treated (as control). Then we performed (phospho) proteome analysis as well as bioinformatic analysis.
ORGANISM(S): Mus Musculus 
2021-08-04 | PXD027693 |
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