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ProteomicsIntegrated Proteomics Characterization of SARS-CoV-2 Associated Liver Injury
The high incidence of liver injury in patients with COVID-19 and the need for long-term medication for recovery make it imperative to study the infectivity and pathogenicity of SARS-CoV-2 in the liver. Here, we have identified significant proteomic changes for the first time in the liver of patients...
ORGANISM(S): Homo Sapiens 
2020-06-23 | PXD019968 |
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
ProteomicsApplication of an iPSC-derived Organoid Model for Located Scleroderma Therapy
Scleroderma is a chronic connective tissue disease characterized by skin thickening and plaque morphea, as well as hard, shiny skin. Serious involvement is observed from the superficial dermis down to the fascia and muscle. However, this condition is difficult to treat and evaluate. In this study, i...
ORGANISM(S): Mus Musculus 
2021-04-26 | PXD025613 |
ProteomicsProteomics Characterization of COVID-19 lung tissues
The COVID-19 pandemic has emerged as a global health emergency due to its association with severe pneumonia and relative high mortality. However, the molecular characteristics and pathological features underlying COVID-19 pneumonia remain largely unknown. To characterize molecular mechanisms underly...
ORGANISM(S): Homo Sapiens 
2020-03-19 | PXD018094 |
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