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Human cerebral microvascular endothelial cells (HCMECs) were infected with extraintestinal pathogenic Escherichia coli (ExPEC) strain RS218 at a multiplicity of infection (MOI) of 1 for 3 hours. Proteomic analysis was performed to evaluate host cellular responses. Infected samples were compared to u...
ORGANISM(S): Homo sapiens (Human) 
2026-04-28 | PXD066627 | Pride
Cells were lysed with TFA, and precipitated with cold acetone. The precipitates were transferred to E3filters and digestion was performed overnight with trypsin. The peptides were desalted with StageTips, and were analyzed on Eclipse Orbitrap with DIA mode. For MS1, the resolution was set to 120,00...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-02-27 | MSV000094179 | MassIVE
This project primarily investigates the interactome of SNX18, a key mediator protein in the degradation of extracellular vesicles (EVs), as well as the degradation efficiency of EGFR and PDL1 using an SNX18-LIR motif-based overexpression platform for targeted protein degradation.
ORGANISM(S): Homo Sapiens 
2025-12-22 | PXD072326 |
Intracerebral hemorrhage (ICH) remains a major cause of morbidity and mortality, with no rapid blood-based biomarkers available to assess secondary brain injury. This study aimed to identify a circulating pan-cell death protein signature for diagnosing and prognosing ICH. We prospectively enrolled 6...
ORGANISM(S): Homo Sapiens 
2025-12-11 | PXD071856 |
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