Sort   by:  
 Page size 
GenomicsCAPRIN1 links embryonic stem cell differentiation with RNA metabolism
CAPRIN1 links embryonic stem cell differentiation with RNA metabolism
PRJNA741829 | ENA
TranscriptomicsCAPRIN1 links embryonic stem cell differentiation with RNA metabolism
Embryonic stem cells (ESCs) are self-renewing and pluripotent. In recent years, factors controlling pluripotency, mostly nuclear, have been identified. To reveal non-nuclear regulators of ESCs, we screened an endogenously-labelled fluorescent fusion-protein library in mouse ESCs. One of the more com...
ORGANISM(S): Mus musculus 
2022-11-18 | GSE179002 | GEO
ProteomicsSmall-molecule degraders of SUMO1 induce the protein ubiquitination and degradation through CAPRIN1-CUL1-FBXO42 ubiquitin ligase for cancer therapySmall-molecule degraders of SUMO1 induce the protein ubiquitination and degradation through CAPRIN1-CUL1-FBXO42 ubiquitin ligase for cancer therapy
Targeted protein degradation has been a long sought, but elusive, strategy for discovery of small-molecule degraders that activate E3 ubiquitin ligase-mediated ubiquitination and degradation of targeted proteins in cancer cells. Here, we report a cancer cell-based drug screen in the discovery of sma...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD022399 | Pride
Cancer Caprin1 Fbxo42 Cul1 e3 ligase Hct116 Ubiquitination Sumo1 Crispr-cas9 E3 ubiquitin ligase Sumoylation 
UnknownCAPRIN1 haploinsufficiency causes a neurodevelopmental disorder with language impairment, ADHD and ASD.
Not available
S-EPMC10169411 | biostudies-literature
UnknownRNA degradation eliminates developmental transcripts during murine embryonic stem cell differentiation via CAPRIN1-XRN2.
Not available
S-EPMC9796812 | biostudies-literature
UnknownAtomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates.
Not available
S-EPMC11363255 | biostudies-literature
UnknownDownregulated miR-621 promotes cell proliferation via targeting CAPRIN1 in hepatocellular carcinoma.
Not available
S-EPMC6220141 | biostudies-literature
UnknownNAT10 promotes ovarian cancer cell migration, invasion, and stemness via N4-acetylcytidine modification of CAPRIN1.
Not available
S-EPMC11806784 | biostudies-literature
UnknownMapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory.
Not available
S-EPMC9457416 | biostudies-literature
UnknownSTRESS granule-associated RNA-binding protein CAPRIN1 drives cancer progression and regulates treatment response in nasopharyngeal carcinoma.
Not available
S-EPMC9750908 | biostudies-literature
Sort   by:  
 Page size