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ProteomicsHeimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes : a new player in neural proteome
The dogma “One gene, one protein” is clearly obsolete since cells use alternative splicing and generate multiple transcripts which are translated into protein isoforms, but also use alternative translation initiation sites (TISs) and termination sites on a given transcripts. Alternative open reading...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-10-24 | PXD042754 | Pride
Immunoglobulin Astrocyte Heimdall Altprot 
ProteomicsAstrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion
Using multi-omics analyses including RNAseq, RT-PCR, RACE-PCR, and shotgun proteomic with enrichment strategies, we demonstrated that newborn rat astrocytes produce neural immunoglobulin constant and variable heavy chains as well as light chains. However, their edification is different from the ones...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-05-10 | PXD040562 | Pride
Immunoglobulins Astrocytes 
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