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ProteomicsExtracellular vesicles from Notch activated cardiac mesenchymal stem cell promote myocyte proliferation and neo-vasculogenesis
Cardiac mesenchymal stem cells (C-MSC) are a novel mesenchymal stem cell subpopulation derived from cardiac tissue, whichi are reported to be responsible for cardiac regeneration. Notch siganling is believed to aid in cardiac repair following myocardial injury.Here, we investigated the difference of...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD016578 | Pride
Mouse Cardiac mesenchymal stem cell Notch1 
TranscriptomicsA Comparison of the Efficacy of Transplantation of Bone Marrow Derived Mesenchymal Stem Cells and Unrestricted Somatic Stem Cells on Outcome After Acute Myocardial Infarction
Unrestricted Somatic Stem Cells (USSC) are a cell population derived from umbilical cord blood. They have been shown to have greater plasticity than mesenchymal stem cells, and are being investigated as a therapeutic option for many disease states, including cardiovascular disease.

In this st...
ORGANISM(S): Homo sapiens 
2012-08-24 | E-MEXP-3638 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Mesenchymal stem cells (MSC) maintained in FCS vs autologous serum analysed at passage 4
The purpose of this study was to determine whether the serum condition affected the gene expression in mesenchymal stem cells (MSCs). To that end, we compared gene expression in MSCs maintained in regular growth medium supplemented with fetal calf serum (FCS) with gene expression of MSCs cultured in...
ORGANISM(S): Homo sapiens 
2004-12-08 | E-MEXP-214 | biostudies-arrayexpress
MetabolomicsZEB1 Maintains Energy Metabolism to Sustain Cardiac Function Through Synergistic Regulation with TEAD1
Metabolic reprogramming plays a critical role in heart failure (HF), but its regulatory mechanisms remain incompletely understood. Zinc finger E-box binding homeobox 1 (ZEB1), a transcription factor initially identified as a regulator of epithelial-mesenchymal transition, has recently been implicate...
2026-09-28 | MTBLS15833 | MetaboLights
TranscriptomicsTranscription profiling of mesenchymal stem cells (MSC) maintained in FCS or autologous serum over time analysed at passage 4 and 10
The purpose of this study was to determine whether the serum condition affected the gene expression in mesenchymal stem cells (MSCs)over time. To that end, we compared gene expression in MSCs maintained in regular growth medium supplemented with fetal calf serum (FCS) for 10 passages with gene expre...
ORGANISM(S): Homo sapiens 
2004-12-08 | E-MEXP-215 | biostudies-arrayexpress
TranscriptomicsTranscription profile of adipose derived mesenchymal stem cells separated by cell surface protein N-cadherin.
Mesenchymal stem cells (MSCs) are one of most promising stem cell sources for regenerative medicine. MSCs have a differention ability into several tissues. However, their differentiation efficiency is considered quite limited. Especially, the differentiation efficiency into cardiomyocytes is very lo...
ORGANISM(S): Homo sapiens 
2013-10-29 | E-GEOD-35232 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion
Fusion of donor mesenchymal stem cells with parenchymal cells of the recipient can occur in the brain, liver, intestine and heart following transplantation. The therapeutic benefit or detriment of resultant hybrids is unknown. Here we sought a global view of phenotypic diversification of mesenchym...
ORGANISM(S): Mus musculus 
2016-03-22 | E-GEOD-69926 | biostudies-arrayexpress
TranscriptomicsGene expression profile of mesenchymal stem cells from paired umbilical cord units: cord is different from blood
Mesenchymal stem cells (MSC) are multipotent cells which can be obtained from several adult and fetal tissues including human umbilical cord units. We have recently shown that umbilical cord tissue (UC) is richer in MSC than umbilical cord blood (UCB) but their origin and characteristics in blood a...
ORGANISM(S): Homo sapiens 
2009-09-18 | E-GEOD-18134 | biostudies-arrayexpress
TranscriptomicsCardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair
Cardiac fibroblasts are critical to proper heart function through multiple interactions with the myocardial compartment. Loosely defined based on their mesenchymal origin, capacity to adhere to plastic and to secrete extracellular matrix, cardiac fibroblasts have been largely neglected due to hetero...
ORGANISM(S): Mus musculus 
2014-05-20 | E-GEOD-50531 | biostudies-arrayexpress
UnknownMechanisms of stem cell based cardiac repair-gap junctional signaling promotes the cardiac lineage specification of mesenchymal stem cells.
Not available
S-EPMC5574972 | biostudies-literature
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