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ProteomicsAnalysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation
HER2 is a transmembrane receptor tyrosine kinase, which plays a key role in breast cancer due to a common genomic amplification. It is used as a marker to stratify patients in the clinic and is targeted by a number of drugs including Trastuzumab and Lapatinib. HER2 has previously been shown to trans...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD003915 | Pride
Breast cancer Rime Her2 
UnknownAdditive Function-on-Function Regression.
Not available
S-EPMC5956967 | biostudies-literature
UnknownUnderstanding desistance from aggression: A joint interpretation of person-centered and variable-centered approaches.
Not available
S-EPMC12752470 | biostudies-literature
ProteomicsTET2 is a component of the ER complex and controls 5mC to 5hmC conversion at ER cis-regulatory regions
Estrogen receptor-alpha (ER) drives tumour development and metastasis in ER positive (ER+) breast cancer. GATA3 is a transcription factor that has been closely linked to ER function, but the role of GATA3 in ER-transcriptional activity is not clear. We sought to identify the contribution of GATA3 to...
ORGANISM(S): Homo sapiens (Human) 
2021-02-10 | PXD019438 | Pride
Breast cancer Estrogen receptor alpha Tet2 Qplex-rime 
UnknownEnhancing Stroke Prevention in Transcatheter Aortic Valve Replacement: The Role of F2, a Novel Neuroprotection Device.
Not available
S-EPMC12686061 | biostudies-literature
Unknown"I Am a Quarterback": A Mixed-Methods Study of Death Investigators' Communication with Family Members of Young Sudden Cardiac Death Victims.
Not available
S-EPMC12925756 | biostudies-literature
TranscriptomicsGene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice
To elucidate the mechanism of BCL6-mediated pre-B cell survival signaling, we investigated the gene expression pattern in BCR-ABL1-transformed BCL6+/+ and BCL6-/- B cell precursors. Pharmacological inhibition of BCR-ABL1 was performed with the BCR-ABL1 kinase inhibitor STI571 (Imatinib). BCR-ABL1 t...
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-20987 | biostudies-arrayexpress
UnknownAssessing the epithelial-to-mesenchymal plasticity in a small cell lung carcinoma (SCLC) and lung fibroblasts co-culture model.
Not available
S-EPMC10022497 | biostudies-literature
UnknownMercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group Study AALL03N1.
Not available
S-EPMC5455766 | biostudies-literature
UnknownMono- versus biarticular muscle function in relation to speed and gait changes: in vivo analysis of the goat triceps brachii.
Not available
S-EPMC2756224 | biostudies-literature
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