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Legionella pneumophila, the causative agent of Legionnaire’s disease, uses its type IV secretion system to translocate over 300 effector proteins into host cells. These effectors subvert host cell signaling pathways to ensure bacterial proliferation. Despite their importance for pathogenesis, the ro...
ORGANISM(S): Homo sapiens (Human) 
2016-02-11 | PXD003573 | Pride
The mechanisms by which the mouse pathogen Citrobacter rodentium triggers effacement of the brush border microvilli, colitis, hyperplasia and dysbiosis remain poorly understood. We investigated the impact of C. rodentium infection on the proteomic and metabolic landscapes of intestinal epithelial ce...
ORGANISM(S): Citrobacter rodentium Mus musculus (Mouse) 
2018-01-10 | PXD005004 | Pride
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