Sort   by:  
 Page size 
ProteomicsPrenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities
The bactericidal function of neutrophils are dependent on myriad intrinsic and extrinsic stimuli. Using systems immunology approaches we identified microbiome- and infection-induced changes in neutrophils. We focused on investigating the Prenylcysteine oxidase 1 like (Pcyox1l) protein function. Muri...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-14 | PXD031115 | Pride
Neutrophil Prenylation Pcyox1l 
TranscriptomicsTranscription profiling of hippocampus and retina from two rare inbred mouse models of accelerated neurological senescence ( SAMP8 and SAMP10) and a related wild type strain SAMR1 to study molecular senescence of the retina and hippocampus.
Background: Progressive neurological dysfunction is a key aspect of human aging. Because of underlying differences in the aging of mice and humans, useful mouse models have been difficult to obtain and study. We have used gene-expression analysis and polymorphism screening to study molecular senesce...
ORGANISM(S): Mus musculus 
2007-11-14 | E-GEOD-6238 | biostudies-arrayexpress
Transcriptomics17b-Trenbolone study
We investigated the genomic transcriptional response of female fathead minnows (Pimephales promelas) to an acute (4 day) exposure to 0.1 or 1.0 µg/L of, 17β-trenbolone (TB), the active metabolite of an anabolic androgenic steroid used as a growth promoter in cattle and a contaminant of concern in ...
ORGANISM(S): Pimephales promelas 
2010-05-14 | E-GEOD-12904 | biostudies-arrayexpress
GenomicsMelanoma Genome Sequencing Project

Melanoma is the most prevalent cause of skin cancer morbidity and mortality. In order to characterize the full range of somatic mutations that may drive the growth of melanoma, we are sequencing tumor and normal DNA from a set of roughly 150 melanomas. For the majority of samples (approximately 9...

phs000452.v1.p1 | EGA
GenomicsProstate Cancer Genome Sequencing Project

Prostate cancer is a prevalent cause of cancer morbidity and mortality in men. In order to characterize the full range of somatic mutations in protein-coding genes that may drive the growth of prostate cancer, we sequenced the exonic regions of genomic and tumor DNA from over 100 patients with hi...

phs000447.v1.p1 | EGA
GenomicsThe Genomic Complexity of Primary Human Prostate Cancer

Seven primary prostate cancers and their paired normal counterparts were DNA-sequenced on a massively parallel sequencing platform. This approach was taken to investigate the genomes for mutations and genomic alterations that would be undetectable by lower-resolution methods. As result, tumor...

phs000330.v1.p1 | EGA
GenomicsWhole Genome and Exon Capture Sequencing of Bladder Cancers

One primary bladder cancer and paired peripheral blood sample were subjected to whole genome sequencing on an Illumina HiSeq 2000 platform. This technology was utilized to investigate the genetic basis of a durable remission of metastatic bladder cancer in a patient treated with everolimus, a dru...

phs000535.v1.p1 | EGA
TranscriptomicsComparative genomic hybridization of 269 individuals from three geographically distinct human populations to investigate copy number variation
We conducted comparative genome hybridization experiments to catalogue the common copy number variation evident between 269 individuals from three geographically distinct human populations (Yoruban, Chinese/Japanese, European) against a single reference individual.
ORGANISM(S): Homo sapiens 
2006-07-31 | E-TABM-107 | biostudies-arrayexpress
UnknownIntegrating health status and survival data: the palliative effect of lung volume reduction surgery.
Not available
S-EPMC2724716 | biostudies-literature
Sort   by:  
 Page size