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TranscriptomicsMolecular Insight into the Association between Cartilage Regeneration and Ear Wound Healing in Genetic Mouse Models: Targeting New Genes in Regeneration
Certain mouse strains have the ability to heal both ear wounds and knee articular cartilage injuries. A positive genetic correlation between cartilage healing and protection from osteoarthritis exists, which suggests that a common core of genes may operate in healing process. Here, we analyzed knee...
ORGANISM(S): Mus musculus 
2013-07-04 | E-GEOD-48505 | biostudies-arrayexpress
ProteomicsFetal immunomodulatory environment following cartilage injury – the key to cartilage regeneration?
Fetal cartilage fully regenerates following injury while in adult mammals cartilage injury leads to osteoarthritis (OA). OA is characterized by cartilage breakdown and joint inflammation and associated with significant pain and socioeconomic costs. As no clinically satisfactory treatment is availabl...
ORGANISM(S): Ovis aries 
2022-02-17 | PXD027486 | Pride
Cartilage Macrophage Regeneration Inflammation Neutrophil Fetal Immunomodulation 
TranscriptomicsThe temporal transcriptomic signature of cartilage formation
To study chondrogenesis, we used a chicken limb bud model: We used RNA sequencing, and examined the differences between gene expression patterns during cartilage formation in micromass cultures of embryonic limb bud-derived progenitors. We sequenced in triplicate at Day 0,1,2,3,4,6,10,15 and also fr...
ORGANISM(S): Gallus gallus 
2023-03-28 | E-MTAB-12770 | biostudies-arrayexpress
ProteomicsProteomic evaluation of decellularization of porcine auricular cartilage
This dataset represents protein profiles of porcine ear cartilage before and after decellularization.
ORGANISM(S): Sus Scrofa Domesticus (ncbitaxon:9825) 
2023-12-15 | MSV000093673 | MassIVE
TranscriptomicsFetal mesenchymal stromal cells differentiating towards chondrocytes acquire a gene expression profile resembling human growth plate cartilage.
We used human fetal bone marrow-derived mesenchymal stromal cells (hfMSCs) differentiating towards chondrocytes as an alternative model for the human growth plate (GP). Our aims were to study gene expression patterns associated with chondrogenic differentiation to assess whether chondrocytes derived...
ORGANISM(S): Homo sapiens 
2013-04-22 | E-GEOD-40942 | biostudies-arrayexpress
ProteomicsComparison of the ability of exosomes and ectosomes derived from mesenchymal stem cells to promote cartilage regeneration in a rat osteochondral defect model
Background: Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) offer promising prospects for stimulating cartilage regeneration. The different formation mechanisms suggest that exosomes and ectosomes possess different biological functions. However, little attention has been paid...
ORGANISM(S): Rattus Rattus 
2023-04-01 | PXD041283 |
MetabolomicsStrontium chelate with Achyranthes bidentata polysaccharide as a carrier promotes bone regeneration through mediating gut-liver-bone axis: The TD chicken model

This study investigates the effect of Achyranthes bidentata polysaccharide-strontium (ABPS-Sr) chelate on tibial dyschondroplasia (TD) in broilers and its underlying mechanisms. TD is a prevalent leg disorder in commercial broilers characterized by reduced angiogenesis in the tibial growth plate ...

2025-09-25 | MTBLS13045 | MetaboLights
MetabolomicsStrontium chelate with Achyranthes bidentata polysaccharide as a carrier promotes bone regeneration through mediating gut-liver-bone axis: The TD chicken model

This study investigates the effect of Achyranthes bidentata polysaccharide-strontium (ABPS-Sr) chelate on tibial dyschondroplasia (TD) in broilers and its underlying mechanisms. TD is a prevalent leg disorder in commercial broilers characterized by reduced angiogenesis in the tibial growth plate ...

2025-09-24 | MTBLS13038 | MetaboLights
GenomicsA requirement for interferon gamma signaling in injury induced cartilage regeneration
A requirement for interferon gamma signaling in injury induced cartilage regeneration
PRJNA970475 | ENA
GenomicsInhibiting Aberrant Interfacial Friction Regulates Cell Fate and Promotes Cartilage Regeneration
Inhibiting Aberrant Interfacial Friction Regulates Cell Fate and Promotes Cartilage Regeneration
PRJNA1392458 | ENA
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