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TranscriptomicsGene expression data from phosphinothricin (PPT) treated Medicago truncatula root nodules
Nitrogen assimilation in plants is a tightly regulated process that integrates developmental and environmental signals. The legume-rhizobial symbiosis results in the formation of a specialized organ called root nodule, where the rhizobia fixes atmospheric nitrogen into ammonia. Ammonia is assimilate...
ORGANISM(S): Medicago truncatula 
2012-05-08 | E-GEOD-34155 | biostudies-arrayexpress
ProteomicsShotgun Imaging Analyzer Gastric Cancer
The data discloses mass spectra of a gastric cancer biopsy sectioned into ten parts, each one subjected to a four step MudPIT analysis (i.e., increasing KCL concentrations of 85, 150, 250, and 400 mM). The biopsy was acquired from an area along the stomach that included tumor and resection margin, d...
ORGANISM(S): Homo sapiens (Human) 
2013-12-05 | PXD000584 | Pride
Gastric cancer lc/lc/ms/ms 
TranscriptomicsTranscriptional profile of bovine chorioallantoic membrane explants in response to wild type, M-NM-^TvirB2 or M-NM-^TbtpB Brucella abortus
In this study the transcription profile of bovine trophoblastic cells infected with Brucella samples was evaluated. Chorioallantoic membrane (CAM) explants inoculated with wild type (strain 2308), and to compare with the transcription profile of trophoblastic cells infected with mutant strains lacki...
ORGANISM(S): Bos taurus 
2014-09-04 | E-GEOD-58216 | biostudies-arrayexpress
ProteomicsCellular and molecular responses of Cryptococcus to brilacidin (MMV1634402) and KIN1400 (MMV019724)
Cryptococcosis is a systemic mycosis caused by Cryptococcus neoformans and C. deuterogattii. Available therapeu-tic options are limited and face several challenges, including high toxicity, the emergence of resistant strains, high costs, and restrict-ed distribution. In this study, we evaluated the ...
ORGANISM(S): Cryptococcus neoformans H99-YPD_1 
2026-09-07 | PXD070309 | Pride
Cryptococcus neoformans Proteomics. Biofilm Cryptococcus deuterogattii Cryptococcosis Antifungal drugs syner-gism Antifungal activity 
ProteomicsClassical virulence factors do not define Cryptococcus pathogenic diversity
Pathogenic determinants in the Cryptococcus genus have been extensively studied, often using standard laboratory isolates. Here, we analyzed the virulence of ten Cryptococcus isolates from diverse sources, species, and genotypes. These isolates exhibited marked differences in their ability to coloni...
ORGANISM(S): Cryptococcus gattii VGII R265 Cryptococcus neoformans var. neoformans JEC21 
2025-10-20 | PXD065863 | Pride
Diversity Virulence Pathogenic Cryptococcus 
TranscriptomicsThe global regulator FfSge1 is required for expression of secondary metabolite gene clusters but not for pathogenicity in Fusarium fujikuroi
The phytopathogenic fungus Fusarium fujikuroi is the causal agent of bakanae disease on rice due to its ability to produce gibberellins. Besides these phytohormones, F. fujikuroi is able to produce a wide range of other secondary metabolites (SMs), such as mycotoxins and pigments. Although much prog...
ORGANISM(S): Fusarium fujikuroi 
2014-10-08 | E-GEOD-53977 | biostudies-arrayexpress
ProteomicsModelling Premature Cardiac Aging with Induced Pluripotent Stem Cells From a Hutchinson-Gilford Progeria Syndrome Patient
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and a high risk of cardiovascular complications. However, the underlying mechanisms of cardiac complications of this syndrome are not fully understood. This study modeled HGPS using cardiomyocytes (C...
ORGANISM(S): Homo sapiens (Human) 
2022-11-10 | PXD036557 | Pride
Progeria Proteomics Ips 
TranscriptomicsTime kinetics of gene expression in NK92 cells after Plasmodium falciparum-iRBC encounter
To study the effect of Plasmodium falciparum-infected erythrocytes on gene expression in NK92 cells, microarray analysis after 6, 12 and 24 hours of co-culture with either uRBC or iRBC was performed. The aim was to identify pathways in NK92 cells that are switched on after iRBC encounter in a time-d...
ORGANISM(S): Homo sapiens 
2011-11-12 | E-GEOD-26876 | biostudies-arrayexpress
ProteomicsUnbiased undepleted malignant pleural effusion proteomics study
Pleural effusion (PE) occurs as a consequence of various pathologies. Malignant effusion due to lung cancer is one of the most frequent causes. Methods for accurate differentiation of malignant from benign PE cases are an unmet clinical need. Proteomics profiling of PE has shown promising results. H...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD035884 | Pride
Pleural effusion Real life clinical cohort Human Biomarker Malignant 
ProteomicsFungal extracellular vesicles are recoverable across variable ultracentrifugation speeds but display species-specific profiles of sedimentation
Extracellular vesicles (EVs) are central components of fungal biology, yet their isolation commonly relies on ultracentrifugation schemes originally developed for mammalian systems. In Cryptococcus, most EVs carry the capsular polysaccharide glucuronoxylomannan (GXM), raising the possibility that ve...
ORGANISM(S): Cryptococcus neoformans RCT29 
2026-06-29 | PXD076414 | Pride
Fungal extracellular  vesicles  ultracentrifugation  profiles 
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