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UnknownMolecular classifications of gastric cancers: Novel insights and possible future applications.
Not available
S-EPMC5434387 | biostudies-literature
TranscriptomicsGenome-wide mRNA expression analyses revealed dysregulation of genes important for SAN function in Hcn4-CreERT2;Isl1 mutants.
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-24 | E-GEOD-69097 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Huntington disease and control cerebral organoids at day 45 and 105 of differentiation
We compared transcriptional profile of organoids derived from iPS lines of a Huntington patient (Q109) and CTR (Q21) at day 45 and day 105 of differentiation.
ORGANISM(S): Homo sapiens 
2018-04-05 | E-MTAB-5964 | biostudies-arrayexpress
GenomicsGenome-wide chromatin-immunoprecipitation studies of purified SAN cells reveals critical direct targets of ISL1 and suggests potential co-factor families for ISL1 action in SAN cells
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-68974 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of the human fetal neocortex, lateral ganglionic eminence and medial ganglionic eminence at 7, 9, 11 and 20 post-conceptional weeks
Deep transcriptional profiling of the human neocortex, lateral ganglionic eminence (LGE) and medial ganglionic eminences (MGE), from 7 to 20 post-conceptional weeks (pcw), for de novo lincRNAs discovery and to establish a unique coding and non-coding gene signature for the three different regions.
ORGANISM(S): Homo sapiens 
2021-05-13 | E-MTAB-8893 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of the human fetal lateral ganglionic eminence at 7, 9 and 11 post-conceptional weeks
Single-cell RNA-seq of the LGE between 7 and 11 pcw was used to uncover the different cell populations of the developing human striatum and how cells transition from early progenitors to mature medium spiny neuron (MSNs) together with the discovery of their unique coding and non-coding transcription...
ORGANISM(S): Homo sapiens 
2021-05-13 | E-MTAB-8894 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression analysis of undifferentiated mouse embryonic stem cells (mES), neonatal mouse cardiomyocytes (CMp) and adult mouse cardiomyocytes (CMa)
Genome-wide gene expression analysis at different stages of cardiomyocyte differentiation (undifferentiated mouse embryonic stem cells, neonatal mouse cardiomyocytes and adult mouse cardiomyocytes). Results provide important information on the differential expressed genes between undifferentiated ...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-44829 | biostudies-arrayexpress
TranscriptomicsEvidence of Distinct Tumor Initiating Cells with Different Properties in Primary Human Hepatocellular Carcinoma.
Increasing evidences have been recently reported on tumor cells heterogeneity within several malignancies, but data on liver tumours are still lacking. The aim of this study was to investigate and characterize tumor initiating cell (TIC) compartments within human hepatocellular carcinoma (HCC). Afte...
ORGANISM(S): Homo sapiens 
2010-10-02 | E-GEOD-24482 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of hESC (H9) lines exposed to a striatal differentiation protocol
Use of single-cell transcriptomics to measure how well medium spiny projection neurons, derived from human ESC, recapitulate human striatal development in vivo. This in vitro single-cell dataset was derived after exposing hESC lines (H9) to a novel striatal differentiation protocol and performing si...
ORGANISM(S): Homo sapiens 
2023-01-31 | E-MTAB-12080 | biostudies-arrayexpress
UnknownAssociation of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes.
Not available
S-EPMC6280443 | biostudies-literature
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