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MetabolomicsNon-targeted metabolomics analysis of synovial fluid from TMD patients
This study performed non-targeted metabolomics detection on 62 human joint cavity lavage fluid samples using UHPLC-QE-MS. Metabolites were extracted with methanol:acetonitrile (1:1), separated on a Waters ACQUITY UPLC BEH Amide column, and detected by Orbitrap Exploris 120 mass spectrometer in both ...
2026-09-23 | MTBLS14238 | MetaboLights
MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
TranscriptomicsDynamics of Virus-specific CD8+ T cells in the Human Nasal Cavity
The goal of this experiment is to compare the transcriptomic profile of CD8+ T cells isolated from the nasal cavity and whole blood at two different state, baseline and CD3/28 activated. This will allow us to characterise the unique features of CD8+ T cells in the nasal cavity. We isolated CD8+CD4...
ORGANISM(S): Homo sapiens 
2025-08-23 | E-MTAB-15436 | biostudies-arrayexpress
ProteomicsProteomic profiling of paired interstitial fluids revealed dysregulated pathways and salivary NID1 as a biomarker of oral cavity squamous cell carcinoma
Patients with oral cavity squamous cell carcinoma (OSCC) are frequently first diagnosed at an advanced stage, leading to poor prognosis and high mortality rate. Early detection of OSCC using body fluid-accessible biomarkers may help improve the prognosis and survival rate of OSCC patients. As tumor ...
ORGANISM(S): Homo sapiens (Human) 
2019-08-15 | PXD008654 | Pride
Tumor interstitial fluid Saliva Oral cavity squamous cell carcinoma Aminoacyl trna biosynthesis Nidogen-1 Biomarker 
TranscriptomicsOral Cavity Cancer Compared to Adjacent "Normal" Tissue [Validation Set]
Oral Cavity Cancer Comparative analysis of gene expression using Affymetrix U133 plus 2.0 microarrays to compare differences between oral cancer samples (most HPV-) and adjacent "normal" mucosa. We have 24 matched pairs of tumor and normal from the same patient
ORGANISM(S): Homo sapiens 
2012-12-05 | E-GEOD-42743 | biostudies-arrayexpress
ProteomicsCerebrospinal Fluid Proteomics of Aging Rats with Depression
Based on the proteomics of cerebrospinal fluid, this study aimed to explore the core pathway and potential targets of luteolin treatment on late-onset depression.
ORGANISM(S): Rattus norvegicus (Rat) 
2023-03-11 | PXD038159 | Pride
Late-onset depression  luteolin  cerebrospinal fluid  proteomics  axon guidance  gsea  aging  ephs  ephrin  semaphorin  netrin  unc5 
TranscriptomicsGene expression changes in Porphyromonas gingivalis W83 after inoculation in rat oral cavity
The aim of this study is to investigate the alterations in gene expression in Porphyromonas gingivalis W83 after inoculation in rat oral cavity. P.gingivalis W83 inoculation in rat oral cavity caused inflammatory responses in gingival tissues and destroyed host alveolar bone. Microarray analysis rev...
ORGANISM(S): Porphyromonas gingivalis W83 
2015-04-07 | E-GEOD-67608 | biostudies-arrayexpress
TranscriptomicsNID2 and HOXA9 promoter hypermethylation as biomarkers to prevent and detect Oral Cavity Squamous Cell Carcinoma
Differentially methylated oral squamous cell carcinoma (OSCC) biomarkers, identified in-vitro and validated in well-characterized surgical specimens, have shown poor clinical correlation in cohorts with different risk profiles. To overcome this lack of relevance we used the HumanMethylation27 BeadCh...
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-28217 | biostudies-arrayexpress
ProteomicsThe protein profiles of washes from the body cavity of Gasterosteus aculeatus L., infected with the Schistocephalus solidus, and from the surface of the helminth
The aim of this study was to describe the excretory–secretory proteins from the helminth Schistocephalus solidus and its intermediate host, the three-spined stickleback Gasterosteus aculeatus L., which are likely to be involved in interactions between them. Combined samples of washes from the G. acu...
ORGANISM(S): Schistocephalus solidus Gasterosteus aculeatus (Three-spined stickleback) 
2024-02-02 | PXD049088 | Pride
Gasterosteus aculeatus Host–parasite interaction Schistocephalus solidus Proteomics Excretory–secretory proteins 
TranscriptomicsA platform of patient-derived tumor xenografts (EOC-xenografts) to recapitulate the clinicopathology and genetic alterations of ovarian cancer
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. On the basis of its histopathology and molecular-genomic changes ovarian cancer has been divided into subtypes, each with distinct biology and outcome. The aim of this study was to develop a panel of patient-derived EOC-xen...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-56920 | biostudies-arrayexpress
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