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Removal of introns during pre-mRNA splicing, which is central to gene expression, initiates by base pairing of U1 snRNA with a 5' splice site (5'SS). In mammals, many introns contain weak 5'SSs that are not efficiently recognized by the canonical U1 snRNP, suggesting alternative mechanisms exist. He...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-07 | PXD029392 | Pride
Removal of introns during pre-mRNA splicing, which is central to gene expression, initiates by base pairing of U1 snRNA with a 5' splice site (5'SS). In mammals, many introns contain weak 5'SSs that are not efficiently recognized by the canonical U1 snRNP, suggesting alternative mechanisms exist. He...
ORGANISM(S): Mus musculus 
2023-05-04 | GSE179744 | GEO
Novel RNA-binding Proteins Bind U1 snRNA to Promote Splicing of Weak 5' Splice Sites
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