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TranscriptomicsTranscription profiling by array of human astrocytes derived from trisomic human embryonic stem cells
Astrocytes derived from normal and aneuploid human embryonic stem cells, along with CCF-STTG1 astrocytoma cell line, and using three biological replicates for each sample, were used to develop an in-vitro model system, to identify biomarkers for astrocytic cancer cells and premalignant stem-like pro...
ORGANISM(S): Homo sapiens 
2010-06-01 | E-MEXP-2633 | biostudies-arrayexpress
ProteomicsIdentification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein metabolism, leads to a rapid inhibition of most protein synthesis, and the induction of protein chaperones. Using heat-shock in cells of neuronal (SH-SY5Y) and glial (CCF-...
ORGANISM(S): Homo sapiens (Human) 
2016-04-11 | PXD003914 | Pride
Detergent insoluble Sh-sy5y Heatshock Ccf-sttg1 Cultured cell 
ProteomicsIdentification of Aryl Hydrocarbon Receptor (AhR) as a Functional Target that Enhances Astrocytic ApoE Secretion
We discovered a chemical series that enhances ApoE secretion from human astrocytes through mechanisms independent of LXR agonism. Using chemoproteomics, photoaffinity probes, KINOMEscan analysis, and siRNA knockdowns, we identified the aryl hydrocarbon receptor (AhR), a transcription factor not prev...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD071908 | Pride
Target id Lc-ms/ms 
UnknownIdentification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes.
Not available
S-EPMC5012716 | biostudies-literature
UnknownThe Effect of Ethanolic Extract of Brazilian Green Propolis and Artepillin C on Cytokine Secretion by Stage IV Glioma Cells Under Hypoxic and Normoxic Conditions.
Not available
S-EPMC11944379 | biostudies-literature
UnknownHuman iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models.
Not available
S-EPMC5918339 | biostudies-literature
UnknownEvaluating the Antitumor Potential of Cannabichromene, Cannabigerol, and Related Compounds from <i>Cannabis sativa</i> and <i>Piper nigrum</i> Against Malignant Glioma: An In Silico to In Vitro Approach.
Not available
S-EPMC12192948 | biostudies-literature
UnknownClusterin Deficiency Promotes Cellular Senescence in Human Astrocytes.
Not available
S-EPMC11953114 | biostudies-literature
UnknownTranscription profiling by array of human astrocytes derived from trisomic human embryonic stem cells
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-MEXP-2633 | biostudies-other
UnknownApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis.
Not available
S-EPMC12616577 | biostudies-literature
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