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ProteomicsPhosphoproteomics of osteoclast differentiation in NT and CD300ld KO RAW264.7 cells
This dataset contains mass spectrometry–based phosphoproteomics of murine RAW264.7 macrophage cells comparing non-targeting control (NT) and CD300ld knockout (CD300ld KO) lines following in vitro osteoclast differentiation. Cells were induced toward osteoclasts using the standard RANKL-driven differ...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-20 | PXD073705 | Pride
Raw264.7 Tmt Osteoclast differentiation Cd300ld Phosphoproteomics Lc-ms/ms 
GenomicsTranscriptome comparsion of WT and CD300ld KO PMN-MDSC
Transcriptome comparsion of WT and CD300ld KO PMN-MDSC
PRJNA820787 | ENA
TranscriptomicsTranscriptome comparsion of WT and CD300ld KO PMN-MDSC
Polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC), also named pathologically activated neutrophil, is a critical component of tumor microenvironment (TME), playing crucial roles in tumor progression and therapy resistance. CD300ld is specifically expressed in normal neutrophils and is upr...
ORGANISM(S): Mus musculus 
2023-06-26 | GSE199602 | GEO
UnknownCD300ld blockade overcomes PMN-MDSC-mediated vaccine resistance in advanced tumors.
Not available
S-EPMC12815194 | biostudies-literature
GenomicsCD300ld regulates tumor immunity
CD300ld regulates tumor immunity
PRJNA820780 | ENA
UnknownFunctional receptor molecules CD300lf and CD300ld within the CD300 family enable murine noroviruses to infect cells.
Not available
S-EPMC5068309 | biostudies-literature
Genomics
Tumor immune microenvironment comparison between WT and CD300ld knockout
PRJNA988305 | ENA
UnknownSono-triggered endoplasmic reticulum-targeted ROS burst silencing CD300ld to alleviate polymorphonuclear myeloid-derived suppressor cells for breast cancer treatment.
Not available
S-EPMC12751942 | biostudies-literature
GenomicsCD300ld regulates tumor immunity - In vivo Crispr-Cas9 screening
CD300ld regulates tumor immunity - In vivo Crispr-Cas9 screening
PRJNA820786 | ENA
TranscriptomicsPathologically Activated Neutrophils Induce Contact-Dependent Suppression of Cytotoxic T Cells
The immunosuppressive tumor microenvironment remains a major obstacle to successful immunotherapy. Pathologically activated neutrophils, alternatively termed polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs), drive tumor immune evasion principally through induction of CD8+ T cell tolera...
ORGANISM(S): Mus musculus 
2026-03-26 | GSE295996 | GEO
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