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ProteomicsPhosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55
Protein phosphatase regulatory subunits are increasingly recognized as promising drug targets. In the absence of an existing drug, inducible degradation provides a means of predicting candidate targets. We here employed auxin-inducible degradation of S. cerevisiae PP2A regulatory subunit Cdc55 in co...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-10-15 | PXD019481 | Pride
Degron Protein phosphatase Silac Pp2a Phosphoproteomics Lc-msms 
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 [Time course 1]
The yeast PP2A-Cdc55 Serine/Threonine phosphatase regulates transcription under certain conditions. It is required for full activation of the environmental stress response mediated by the transcription factors Msn2 and Msn4. PP2A-Cdc55 contributes to sustained nuclear accumulation of Msn2 and Msn4 a...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-08 | GSE38565 | GEO
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 [Time course 2]
The yeast PP2A-Cdc55 Serine/Threonine phosphatase regulates transcription under certain conditions. It is required for full activation of the environmental stress response mediated by the transcription factors Msn2 and Msn4. PP2A-Cdc55 contributes to sustained nuclear accumulation of Msn2 and Msn4 a...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae W303 
2012-11-06 | GSE42033 | GEO
UnknownPP2A-Cdc55 phosphatase regulates actomyosin ring contraction and septum formation during cytokinesis.
Not available
S-EPMC8888506 | biostudies-literature
UnknownDual Regulation of the mitotic exit network (MEN) by PP2A-Cdc55 phosphatase.
Not available
S-EPMC3854864 | biostudies-literature
TranscriptomicsExpression of AWR5 in wild type and cdc55 deletion mutant at 6 h of induction
Expressing the type III effector AWR5 of the phytopathogen Ralstonia solanacearum in yeast cells causes cessation of growth and transcriptional changes reminiscent of inhibition of the TOR pathway. Deletion of cdc55, a regulatory subunit of the PP2A Ser/Thr protein phosphatase eliminates the strong ...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-31 | GSE70331 | GEO
ProteomicsPhosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55
Protein phosphatase regulatory subunits are increasingly recognized as promising drug targets. In the absence of an existing drug, inducible degradation provides a means of predicting candidate targets. We here employed auxin-inducible degradation of S. cerevisiae PP2A regulatory subunit Cdc55 in co...
ORGANISM(S): Saccharomyces Cerevisiae 
2021-01-27 | PXD019534 | panorama
TranscriptomicsExpression of AWR5 in wild type and cdc55 deletion mutant at 6 h of induction
Expressing the type III effector AWR5 of the phytopathogen Ralstonia solanacearum in yeast cells causes cessation of growth and transcriptional changes reminiscent of inhibition of the TOR pathway. Deletion of cdc55, a regulatory subunit of the PP2A Ser/Thr protein phosphatase eliminates the strong ...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-31 | E-GEOD-70331 | biostudies-arrayexpress
TranscriptomicsThe yeast PP2A-CDC55 phosphatase regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4
The yeast PP2A-Cdc55 Serine/Threonine phosphatase regulates transcription under certain conditions. It is required for full activation of the environmental stress response mediated by the transcription factors Msn2 and Msn4. PP2A-Cdc55 contributes to sustained nuclear accumulation of Msn2 and Msn4 a...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-07 | E-GEOD-38565 | biostudies-arrayexpress
ProteomicsSILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast.
Protein phosphatase 2A (PP2A) is a family of conserved serine/threonine phosphatases involved in several essential aspects of cell growth and proliferation. PP2ACdc55 phosphatase has been extensively related to cell cycle events in budding yeast, however few PP2ACdc55 substrates have been identified...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-04-16 | PXD007613 | Pride
Pkc1 Mob1. Mitotic exit network (men) Pp2acdc55 phosphatase Cla4 
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