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ProteomicsCDH11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit
The molecular etiology of numerous risk genes for autism spectrum disorder (ASD), including CDH11, remains elusive. We investigated the role of CDH11 in the development of ASD-related behaviors using gene-deficient mice. CDH11 is enriched at synapses in glutamatergic neurons of the anterior cingulat...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-08 | PXD056411 | Pride
Synaptic adhesion Asd Neuronal activity Proteomics Brain circuit Self-grooming Cdh11 Acc 
GenomicsscRNA-seq of fibroblasts from inducible Cdh11 reporter mice
scRNA-seq of fibroblasts from inducible Cdh11 reporter mice
PRJNA1434525 | ENA
TranscriptomicsNext Generation Sequencing identifies Cdh11 and Mrc1 as novel translational biomarkers of kidney fibrosis
Chronic kidney disease (CKD) is the gradual, asymptomatic loss of kidney function and current tests only identify it when significant loss has already happened. Using RNA sequencing in a mouse model of folic acid (FA) induced nephropathy, here we report the identification of 10 genes that track kidn...
ORGANISM(S): Mus musculus 
2015-10-23 | E-GEOD-65267 | biostudies-arrayexpress
ProteomicsCDH11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit
The molecular etiology of numerous risk genes for autism spectrum disorder (ASD), including CDH11, remains elusive. We investigated the role of CDH11 in the development of ASD-related behaviors using gene-deficient mice. CDH11 is enriched at synapses in glutamatergic neurons of the anterior cingulat...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-08 | PXD055834 | Pride
Synaptic adhesion Asd Neuronal activity Proteomics Brain circuit Self-grooming Cdh11 Acc 
ProteomicsCDH11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit
The molecular etiology of numerous risk genes for autism spectrum disorder (ASD), including CDH11, remains elusive. We investigated the role of CDH11 in the development of ASD-related behaviors using gene-deficient mice. CDH11 is enriched at synapses in glutamatergic neurons of the anterior cingulat...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-08 | PXD056074 | Pride
Synaptic adhesion Asd Neuronal activity Proteomics Brain circuit Self-grooming Cdh11 Acc 
GenomicsSingle cell level characterization of Cdh11 deficiency-induced changes in pancreatic cancer
Single cell level characterization of Cdh11 deficiency-induced changes in pancreatic cancer
PRJNA978564 | ENA
GenomicsCDH11 contributes to bladder cancer progression via regulation of mitochondrial energy metabolism.
CDH11 contributes to bladder cancer progression via regulation of mitochondrial energy metabolism.
PRJNA1160278 | ENA
TranscriptomicsscRNA-seq of fibroblasts from inducible Cdh11 reporter mice
Cadherin 11 (Cdh11) is a member of the cadherin superfamily, a group of transmembrane proteins that are principally located in adheren junctions and mediate cell-to-cell adhesion. Dysregulation of Cdh11 in fibroblast populations has been associated with pathologic processes such as inflammation, fib...
ORGANISM(S): Mus musculus 
2026-05-05 | GSE324380 | GEO
TranscriptomicsSingle cell level characterization of Cdh11 deficiency-induced changes in pancreatic cancer
Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been suggested to promote tumor growth and immunosuppression in PDAC, and Cdh11 inhibition significantly extended survival in mice with PDAC. However, the mechanisms by which Cdh11 deficiency influences PDAC progression and anti-tumor immune...
ORGANISM(S): Mus musculus 
2025-05-01 | GSE233915 | GEO
GenomicsFOXF1 inhibits pulmonary fibrosis by preventing CDH2-CDH11 cadherin switch in myofibroblasts
FOXF1 inhibits pulmonary fibrosis by preventing CDH2-CDH11 cadherin switch in myofibroblasts
PRJNA433652 | ENA
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