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ProteomicsMulti-omics, multi assay analysis of evolved resistance to ceftazidime-avibactam in Pseudomonas aeruginosa, compared to meropenem resistance and co-resistance evolution
Pseudomonas aeruginosa is a major cause of infection in hospitalised patients, with a large genome which makes it highly versatile and resistant to most antimicrobial agents. Ceftazidime-avibactam (CZA) offers an alternative treatment, but resistance is quickly evolving. There is limited knowledge ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-05-21 | PXD044998 | Pride
Proteomics Crispr/cas9 Ceftazidime-avibactam Resistance mechanism Pseudomonas aeruginosa Genomics Transcriptomics Dacb Meropenem 
GenomicsWhole-Genome Sequencing of Ceftazidime-Avibactam resistant KPC-producing Klebsiella pneumoniae strains
Emergence of Ceftazidime-Avibactam resistant KPC-producing K. pneumoniae (KPC-Kp) during ceftazidime-avibactam-based antimicrobial treatment.
PRJEB21871 | ENA
GenomicsSusceptibility to ceftazidime/avibactam in German MDR/XDR Pseudomonas aeruginosa
Susceptibility to ceftazidime/avibactam in German MDR/XDR Pseudomonas aeruginosa
PRJEB30639 | ENA
GenomicsCeftazidime-Avibactam plus Aztreonam Cocktail for the Treatment of VIM-Producing Pseudomonas aeruginosa Infections.
Ceftazidime-Avibactam plus Aztreonam for the Treatment of VIM-Producing Pseudomonas aeruginosa Infections.
PRJEB81449 | ENA
GenomicsLaboratory-selected mutants of Enterobacteriaceae with resistance or diminished susceptibility to ceftazidime/avibactam
Selection of mutants with resistance or diminished susceptibility to ceftazidime/avibactam from ESBL- and AmpC- producing Enterobacteriaceae
PRJEB27344 | ENA
UnknownCeftazidime-Avibactam Therapy Versus Ceftazidime-Avibactam-Based Combination Therapy in Patients With Carbapenem-Resistant Gram-Negative Pathogens: A Meta-Analysis.
Not available
S-EPMC8476997 | biostudies-literature
GenomicsSystematic evaluation of in vitro pharmacodynamic drug interactions of ceftazidime/avibactam and fosfomycin in E. coli
Systematic evaluation of in vitro pharmacodynamic drug interactions of ceftazidime/avibactam and fosfomycin in E. coli
PRJEB60842 | ENA
UnknownThe β-Lactams Strike Back: Ceftazidime-Avibactam.
Not available
S-EPMC4545577 | biostudies-literature
UnknownCeftazidime/Avibactam Resistance in Carbapenemase-Producing Klebsiella pneumoniae.
Not available
S-EPMC10617341 | biostudies-literature
GenomicsCeftazidime-avibactam use selects multidrug-resistance and prevents designing collateral sensitivity-based therapies against Pseudomonas aeruginosa
Ceftazidime-avibactam use selects multidrug-resistance and prevents designing collateral sensitivity-based therapies against Pseudomonas aeruginosa
PRJEB85283 | ENA
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