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TranscriptomicsTranscription profiling of mouse bipotential embryonic liver cells to identify liver progenitor cell surface markers.
This SuperSeries is composed of the following subset Series:; GSE6942: Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers (moe430a). GSE6957: Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6966 | biostudies-arrayexpress
ProteomicsComprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes
Monocytes are a critical component of the cellular innate immune system, and can be subdivided into classical, intermediate and non-classical subsets on the basis of surface CD14 and CD16 expression. Classical monocytes play the canonical role of phagocytosis, and account for the majority of circula...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD013832 | Pride
Classical monocyte Monocyte Blood cell Cell surface Quantitative proteomics Tandem mass tag Plasma membrane 
TranscriptomicsTranscription profiling of mouse bipotential embryonic liver cells to identify liver progenitor cell surface markers (430)
The ability to purify to homogeneity a population of hepatic progenitor cells from adult liver is critical for their characterization prior to any therapeutic application. As a step in this direction, we have utilized gene profiling of a bipotential liver cell line from dpc 14 mouse embryonic liver...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6957 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse bipotential embryonic liver cells to identify liver progenitor cell surface markers (430A)
The ability to purify to homogeneity a population of hepatic progenitor cells from adult liver is critical for their characterization prior to any therapeutic application. As a step in this direction, we have utilized gene profiling of a bipotential liver cell line from dpc 14 mouse embryonic liver...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6942 | biostudies-arrayexpress
MetabolomicsN-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein glycosylation. CRC cell lines are frequently used to study these (glyco)biological changes and their mechanisms. However, differences between CRC cell lines with regard to their glycosylation have hitherto bee...
2017-02-03 | MTBLS227 | MetaboLights
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
MetabolomicsThe Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. Numerous ultrastructural studies have documented a plasma membrane invagination with a d...

2023-04-19 | MTBLS7006 | MetaboLights
TranscriptomicsHIT: a new versatile protein array platform for multi-analyte phenotyping of surface molecules
We have developed a multi-analyte fluid-phase protein array technology termed high-throughput immunophenotyping using transcription (HIT). This method employs a panel of monoclonal antibodies, each tagged with a unique oligonucleotide sequence that serves as a molecular barcode. After staining a s...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10665 | biostudies-arrayexpress
ProteomicsData in support of the equine mesenchymal stem cell surface proteome for mining for new surface markers
Regenerative medicine in aims to restore structure and function to tissues or organs damaged by time, disease or injury. Stem cells have great potential for tissue repair and regeneration, why they are intensely investigated in equine clinical research. However, before any type of stem cell can be a...
ORGANISM(S): Equus caballus (Horse) 
2018-11-04 | PXD008884 | Pride
Horse stem cells membrane 
TranscriptomicsDynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns
Human mesenchymal stem cells (hMSCs) are defined as multi-potent colony-forming cells expressing a specific subset of plasma membrane markers when grown on flat tissue culture polystyrene. However, as soon as hMSCs are used for transplantation, they are exposed to a 3D environment, which can strongl...
ORGANISM(S): Homo sapiens 
2019-06-18 | E-MTAB-7505 | biostudies-arrayexpress
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