Sort   by:  
 Page size 
ProteomicsIdentification of ADP-ribosylation targets in living HeLa cells using cell-permeable NAD+ probes
Posttranslational modifications of proteins (PTMs) greatly enhance their functional diversity, surpassing the number of gene-encoded variations. One intriguing PTM is ADP-ribosylation, which utilizes nicotinamide adenine dinucleotide (NAD+) as a substrate and is essential in cell signaling pathways ...
ORGANISM(S): Homo sapiens (Human) 
2024-10-11 | PXD051967 | Pride
Affinity enrichment Hela cells Nad+ Cell-permeable probes Adp-ribosylation 
UnknownNew class of 8-aryl-7-deazaguanine cell permeable fluorescent probes.
Not available
S-EPMC4592842 | biostudies-literature
UnknownA general strategy for developing cell-permeable photo-modulatable organic fluorescent probes for live-cell super-resolution imaging.
Not available
S-EPMC4263135 | biostudies-literature
ProteomicsBiocompatible sulfonium-based covalent probes for endogenous tubulin fluorescence nanoscopy in live and fixed cells
Fluorescent probes enable the visualization of dynamic cellular processes with high precision, particularly when coupled with super-resolution imaging techniques that surpass the diffraction limit. Traditional methods include fluorescent protein fusion (e.g., GFP) or organic fluorophores linked to l...
ORGANISM(S): Sus Scrofa (ncbitaxon:9823) 
2025-11-18 | MSV000099944 | MassIVE
UnknownProfiling Serine Hydrolases in the Leishmania Host-Pathogen Interactome Using Cell-Permeable Activity-Based Fluorophosphonate Probes.
Not available
S-EPMC12117450 | biostudies-literature
TranscriptomicsTranscription profiling of Mia PaCa-2 cancer cells treated with a cell-permeable RAS inhibitor and its negative control
The action mechanism of a cell-permeable RAS inhibitor (Pen-cRaf-v1) and its binding-disrupting mutant (Pen-cRaf-v1-AA) was studied by transcription profiling of Mia PaCa-2 cancer cells treated with the inhibitors at the concentration of 10 microM for 3 hours.
ORGANISM(S): Homo sapiens 
2021-06-01 | E-MTAB-10403 | biostudies-arrayexpress
UnknownSingle Atom Stabilization of Phosphinate Ester-Containing Rhodamines Yields Cell Permeable Probes for Turn-On Photoacoustic Imaging.
Not available
S-EPMC10926271 | biostudies-literature
ProteomicsDevelopment of inhibitors, probes, and PROTAC provides a complete toolbox to study PARK7 in the living cell
The innovation of combined chemical tools, such as small molecule inhibitors, activity-based probes (ABPs), and proteolysis targeting chimeras (PROTACs) for a specific target, not only advances clinical drug discovery but also provides a chemical toolbox to study the diverse biological perspective o...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD047093 | Pride
Park7 Small molecule inhibitors Protacs Activity-based probes 
UnknownControlling Intramolecular Rotation with Five-Membered Heterocycles Facilitates the Design of Highly Cell-Permeable Xanthene-Based Fluorogenic Probes.
Not available
S-EPMC12766722 | biostudies-literature
UnknownA cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1.
Not available
S-EPMC4503230 | biostudies-literature
Sort   by:  
 Page size