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ProteomicsCell Surface Protein Atlas - A mass spectrometric-derived cell surface protein atlas
Cell Surface Capture (Wollscheid et al., 2009, Nat.biotec.) was performed on various different cell types in order to characterize the cell surface proteome and to build the Cell Surface Protein Atlas.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2016-02-16 | PXD000589 | Pride
Cspa Surfaceome Mass spectrometry Cell surface capture 
ProteomicsRB383 retinoblastoma cell line surface proteome
The proteins on the surface of RB383 retinoblastoma cell line were analyzed by cell surface biotinylation and streptavidin affinity purification.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039518 | Pride
Retinoblastoma Cell surface proteome 
ProteomicsY79 retinoblastoma cell line surface proteome
The proteins on the surface of Y79 retinoblastoma cell line were analyzed by cell surface biotinylation and streptavidin affinity purification.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039517 | Pride
Retinoblastoma Cell surface proteome 
TranscriptomicsDynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns
Human mesenchymal stem cells (hMSCs) are defined as multi-potent colony-forming cells expressing a specific subset of plasma membrane markers when grown on flat tissue culture polystyrene. However, as soon as hMSCs are used for transplantation, they are exposed to a 3D environment, which can strongl...
ORGANISM(S): Homo sapiens 
2019-06-18 | E-MTAB-7505 | biostudies-arrayexpress
ProteomicsComprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes
Monocytes are a critical component of the cellular innate immune system, and can be subdivided into classical, intermediate and non-classical subsets on the basis of surface CD14 and CD16 expression. Classical monocytes play the canonical role of phagocytosis, and account for the majority of circula...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD013832 | Pride
Classical monocyte Monocyte Blood cell Cell surface Quantitative proteomics Tandem mass tag Plasma membrane 
ProteomicsTracking drug action on the cell surface proteome
Endogenous ligands and drugs interact with the cell-surface proteome but hypothesis-free tracking of dynamic remodeling processes at the plasma membrane is challenging. We introduce cell surface thermal proteome profiling for comprehensive characterization of ligand-induced changes in protein abunda...
ORGANISM(S): Homo sapiens (Human) 
2020-10-26 | PXD016249 | Pride
Thermal proteome profiling Cell surface Plasma membrane 
ProteomicsCell Surface Glycoengineering - HAP1 Cells
Cell Surface Glycoengineering of HAP1 Cells using CMP-Neu5Ac Derivatives
ORGANISM(S): Homo sapiens (Human) 
2022-06-26 | PXD024251 | Pride
Cell surface glycoengineering - hap1 cells 
TranscriptomicsTranscription profiling of Pseudomonas aeruginosa overexpressing the ECF sigmas PA0149, PA2050, PA2093 and PA4896 involved in cell-surface signaling systems
Cell-surface signaling is a sophisticated regulatory mechanism used by gram-negative bacteria to sense signals from outside the cell and transmit them into the cytoplasm. This regulatory system consists of an outer membrane-localized TonB-dependent receptor (TonB-dependent transducer), a cytoplasmic...
ORGANISM(S): Pseudomonas aeruginosa 
2008-06-16 | E-GEOD-9657 | biostudies-arrayexpress
ProteomicsSurfactant-assisted one-pot sample preparation for label-free single-cell proteomics
Large numbers of cells are generally required for quantitative global proteome profiling due to the significant surface adsorption losses associated with sample processing. Such bulk measurement obscures important cell-to-cell variability (cell heterogeneity) and makes proteomic profiling impossible...
ORGANISM(S): Homo Sapiens 
2021-03-11 | PXD022827 | panorama
ProteomicsA Chemical Proteomics Approach for Global Mapping of Functional Lysines on Cell Surface of Living Cell
Cell surface proteins are responsible for many crucial physiological roles, and they are also the major category of drug targets as the majority of therapeutics target membrane proteins on the surface of cells to alter cellular signaling. How-ever, despite its great significance, ligand discovery ag...
ORGANISM(S): Homo Sapiens 
2024-03-01 | PXD042888 |
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