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ProteomicsRole of cellular retinol-binding protein, type 1 and retinoid homeostasis in the adult mouse heart: a multi-omic approach
The main active metabolite of Vitamin A, all-trans retinoic acid (RA), is responsible for proper cellular function and tissue organization. The role of RA has been extensively studied in development, but there is limited research on its role in the adult heart. Cellular retinol-binding protein, type...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD029349 | Pride
Heart Retinoid metabolism Mice Retinoic acid Cellular retinol binding protein type 1 
Transcriptomicssingle cell RNA sequencing of 120h mouse gastruloids cultured with different doses of retinol
We quantified the effects of retinol on the cell type composition of gastruloids at 120 hours after aggregation by single cell RNA sequencing (scRNA-seq). Gastruloids were generated from the Rarb2.LacZ reporter cell line and cultured according to the standard protocol and few modifications: - cultu...
ORGANISM(S): Mus musculus 
2026-07-24 | E-MTAB-17398 | biostudies-arrayexpress
UnknownQuantitation of the Noncovalent Cellular Retinol-Binding Protein, Type 1 Complex Through Native Mass Spectrometry.
Not available
S-EPMC5728378 | biostudies-literature
UnknownRole of cellular retinol-binding protein, type 1 and retinoid homeostasis in the adult mouse heart: A multi-omic approach.
Not available
S-EPMC9361781 | biostudies-literature
UnknownComparison of retinol binding protein 1 with cone specific G-protein as putative effector molecules in cryptochrome signalling.
Not available
S-EPMC11569197 | biostudies-literature
TranscriptomicsIntragraft transcriptional profiling of renal transplant patients with tubular dysfunction after distinct immunosuppressive regimens
Intragraft transcriptional profiles were investigated in patients with tubular dysfunction to disclose subclinical mechanisms underlying graft deterioration. Moreover, we analyzed whether individualization of immunosuppression could modify this profile while improving renal function after 12 months ...
ORGANISM(S): Homo sapiens 
2015-07-31 | E-GEOD-48250 | biostudies-arrayexpress
TranscriptomicsVitamin A nutritional status and retinoic acid as regulators of gene expression in rat liver
Vitamin A (retinol) is an essential precursor for the production of retinoic acid (RA), which in turn is a major regulator of gene expression, affecting cell differentiation throughout the body. Understanding how vitamin A nutritional status, as well as therapeutic retinoid treatment, regulates the ...
ORGANISM(S): Rattus norvegicus 
2011-08-31 | E-GEOD-24104 | biostudies-arrayexpress
TranscriptomicsEffects of vitamin A on ventricular myocardium gene expression [left ventricle]
LRAT knockout mice on vitamin A sufficient or deficient diets were compared to age and gender matched wildtype mice on a vitamin A sufficient diet RNA was isolated from the left ventricle of the heart and one array was run for each sample.
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-74904 | biostudies-arrayexpress
TranscriptomicsChanges in gene expression in the retina of diabetic Long Evans rats after one, four, and twelve weeks of diabetes
Purpose. Patients with diabetic retinopathy may experience severe vision loss due to macular edema and neovascularization secondary to vascular abnormalities. However, before these abnormalities become apparent, there are functional deficits in contrast sensitivity, color perception, and dark adapta...
ORGANISM(S): Rattus norvegicus 
2011-10-31 | E-GEOD-28831 | biostudies-arrayexpress
UnknownVitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding protein.
Not available
S-EPMC3815300 | biostudies-literature
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