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ProteomicsCEP215_gallus_interactome - A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer
To establish the molecular basis for CEP215 function in centrosome-spindle pole attachment, we employed an unbiased proteomic approach to isolat e and identify CEP215 interactors. To this end, affinity purification tags ( Gs TAP containing protein G and streptavidin-binding pr...
ORGANISM(S): Gallus gallus (Chicken) 
2016-03-31 | PXD003382 | Pride
Hset Cancer Centrosome clustering Centrosome Micr ocephaly Cep215 Mitosis 
UnknownCortical dynein drives centrosome clustering in cells with centrosome amplification.
Not available
S-EPMC10208098 | biostudies-literature
UnknownCentrosome linker diversity and its function in centrosome clustering and mitotic spindle formation.
Not available
S-EPMC10476278 | biostudies-literature
Unknownp53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells.
Not available
S-EPMC3208627 | biostudies-literature
UnknownIFT proteins interact with HSET to promote supernumerary centrosome clustering in mitosis.
Not available
S-EPMC7271317 | biostudies-literature
UnknownA Cancer-Associated Missense Mutation in PP2A-Aα Increases Centrosome Clustering during Mitosis.
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S-EPMC6664223 | biostudies-literature
UnknownOTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival.
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S-EPMC11850729 | biostudies-literature
UnknownThe ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation.
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S-EPMC7782532 | biostudies-literature
UnknownLIMK2 promotes centrosome clustering and cancer progression by activating MST4-mediated phosphorylation of NPM1.
Not available
S-EPMC12436196 | biostudies-literature
UnknownNek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction.
Not available
S-EPMC10944510 | biostudies-literature
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