Sort   by:  
 Page size 
MetabolomicsCeramide Promotes Lytic Reactivation of Epstein-Barr Virus in Gastric Carcinoma
Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...
2023-12-20 | MTBLS7649 | MetaboLights
MetabolomicsClinical Application Value of Ceramide and Sphingomyelin as Biomarkers for the Diagnosis of Drug-Induced Liver Injury

Background : Drug-induced liver injury (DILI) is a serious health concern that presents challenges in early detection and accurate diagnosis, thereby complicating the treatment of this liver disease. Therefore, it is crucial to explore specific biomarkers to improve the accuracy of diagnosing DIL...

2025-07-23 | MTBLS12765 | MetaboLights
ProteomicsLiver proteome upon in vivo N-acetylgalactosamine-conjugated antisense oligonucleotide silencing of ceramide synthase 2
Mouse liver proteome was investigated upon in vivo mouse treatment with a N-acetylgalactosamine-conjugated antisense oligonucleotide engineered to silence ceramide synthase 2 specifically in hepatocytes in vivo. The data is a part of a study on the involvement of ceramide enzymatic machinery in card...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD025957 | Pride
Silencing Liver Mouse Proteome Ceramide synthase 2 
GenomicsAging stress and ceramide dependent RNA sequencing expression profiling depends on ceramide synthase 6
Aging stress and ceramide dependent RNA sequencing expression profiling depends on ceramide synthase 6
PRJNA624654 | ENA
ProteomicsFatty acid transport protein 2 interacts with ceramide synthase 2 to regulate ceramide synthesis
Dihydroceramide is generated via the action of (dihydro)ceramide synthases (CerSs), which use two substrates, namely sphinganine and fatty acyl CoAs. Sphinganine is generated via the sequential activity of two integral membrane proteins located in the endoplasmic reticulum. Less is known about the s...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD031088 | Pride
Ceramide synthase Dihydroceramide Ceramide Fatty acid transport protein Sphingolipids 
TranscriptomicsAging stress and ceramide dependent RNA sequencing expression profiling depends on ceramide synthase 6
The bioactive sphingolipid ceramide, generated by ceramide synthase, is an adaptive stress effector induced in response to various stress stimuli such as aging. In fact, ceramide synthase (CerS) was first discovered in yeast as a longevity assurance gene (LAG1), as the reduced ceramide generation co...
ORGANISM(S): Mus musculus 
2021-01-01 | GSE148498 | GEO
ProteomicsA novel C-terminal DxRSDxE motif in ceramide synthases involved in dimer formation
Ceramide is synthesized via the ceramide synthases (CerSs), six of which have been identified in mammalian cells, with each using a unique subset of acyl-CoAs for ceramide synthesis. The CerSs are part of a larger gene family, the Tram-Lag-CLN8 (TLC) domain family. We now identify a unique, C-termin...
ORGANISM(S): Homo sapiens (Human) 
2022-01-17 | PXD029496 | Pride
Motif Ceramide synthase Ceramide Dimer Sphingolipids 
GenomicsA ceramide synthase is important for filamentous fungal biofilm morphology and antifungal drug susceptibility
A ceramide synthase is important for filamentous fungal biofilm morphology and antifungal drug susceptibility
PRJNA1442198 | ENA
UnknownLip1p: a novel subunit of acyl-CoA ceramide synthase.
Not available
S-EPMC549621 | biostudies-literature
UnknownAll members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.
Not available
S-EPMC4340302 | biostudies-literature
Sort   by:  
 Page size