Identification of common mechanisms underlying organ development and primary tumor formation should yield new insights into tumor biology and facilitate the generation of relevant cancer models. We have developed a novel method to project the gene expression profiles of medulloblastomas (MBs)—human ...
We hypothesized that sexual dimorphism in experimental autoimmune enecphalomyelitis arises from sexually dimorphic and CNS-region specific expression of genes that regulate BBB permeability and leukocyte entry. To test this hypothesis, we profiled total RNA from the cerebella and frontal cortices of...
In this study we performed single-cell sequencing of E13.5 mouse cerebella, revealing different newly generated neurons and their associated molecular features.
To investigate the transcriptomic changes in mouse cerebella with Purkinje cell–specific expression of the STING-N153S mutant, we performed RNA sequencing (RNA-seq) on cerebellar tissue from N153SLSL/LSLPcp2-cre and N153SLSL/LSL mice.
