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A proteomic comparison of the cerebella of APC7 KO mice versus controls using TMT11-plex reagents
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD016683 | Pride
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1/2 to activate YAP/TAZ
Introduction: The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase critically involved in cell cycle regulation. However, the pathological functions of its individual subunits, particularly in hepatocellular carcinoma (HCC), remain largely unexplored. Objectives: T...
ORGANISM(S): Homo sapiens 
2026-05-15 | GSE319107 | GEO
P granules in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency.  Sterility in the absence of P granules is often accompanied by the mis-expression of soma-specific proteins and the initiation of somatic differentiation in germ cells.  To investigate ...
ORGANISM(S): Caenorhabditis elegans 
Argonaute proteins and their small RNA co-factors short interfering RNAs (siRNAs) are known to inhibit gene expression at the transcriptional and post-transcriptional levels. In Caenorhabditis elegans, the Argonaute CSR-1 binds thousands of endogenous siRNAs (endo-siRNAs) antisense to germline trans...
ORGANISM(S): Caenorhabditis elegans 
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