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TranscriptomicsSall4 ChIP-chip in mouse ES cell line W4 using NimbleGen MM8 RefSeq Promoter array (2.5kb)
Embryonic stem cells have potential utility in regenerative medicine due to their pluripotent characteristics. Sall4, a zinc-finger transcription factor, is expressed very early in embryonic development with Oct4 and Nanog, two well characterized pluripotency regulators. Sall4 plays an important rol...
ORGANISM(S): Mus musculus 
2008-09-01 | E-GEOD-11305 | biostudies-arrayexpress
UnknownImproved Survival of Advanced-Stage Anaplastic Thyroid Cancer With Systemic Therapy.
Not available
S-EPMC11635144 | biostudies-literature
UnknownImpact of point-of-care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial.
Not available
S-EPMC12302277 | biostudies-literature
TranscriptomicsSALL4 ChIP-chip using NimbleGen HG18 RefSeq Promoter tiling array (2.7kb)
Increasing studies suggest that SALL4 may play vital roles in leukemogenesis. We have used chromatin immunoprecipitation followed by microarray hybridization as a screening tool to determine potential genes that may account for the role SALL4 plays in leukemogenesis. Analysis of SALL4 binding sites ...
ORGANISM(S): Homo sapiens 
2008-05-17 | E-GEOD-10734 | biostudies-arrayexpress
UnknownA phase 2 study of the BH3 mimetic BCL2 inhibitor navitoclax (ABT-263) with or without rituximab, in previously untreated B-cell chronic lymphocytic leukemia.
Not available
S-EPMC4643417 | biostudies-literature
UnknownPersonalized Kirigami Strain Sensors for in vivo Applications.
Not available
S-EPMC12467391 | biostudies-literature
TranscriptomicsProspective comparison of genome-wide aCGH platforms for the detection of CNVs in MR (Mapping250K_Nsp and Mapping250K_Sty)
Clinical laboratories are adopting array comparative genomic hybridization (AGH) as a standard clinical test. A number of whole genome AGH systems are available, but little is known about the comparative performance in a clinical context. We prospectively studied 30 children with idiopathic MR and ...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-27216 | biostudies-arrayexpress
ProteomicsChemical genetic validation of CSNK2 substrates using an inhibitor-resistant mutant in combination with triple SILAC quantitative phosphoproteomics
Casein Kinase 2 (CSNK2) is an extremely pleiotropic, ubiquitously expressed protein kinase involved in the regulation of numerous key biological processes. Mapping the CSNK2-dependent phosphoproteome is necessary for better characterization of its fundamental role in cellular signalling. While ATP-c...
ORGANISM(S): Homo sapiens (Human) 
2022-07-14 | PXD033523 | Pride
Protein kinase ck2 U2os cells Csnk2 Silac Cx-4945 Phosphoproteomics Lc-ms/ms 
TranscriptomicsDeep Sequence Analysis of non-small cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations
In this manuscript, we have used RNA-Sequencing experiment to obtain and integrate a variety of genomic features in order to identify signaling pathways that are associated to mutant KRAS lung tumors. 8 lung adenocarcinomas with mutant KRAS in lung tumors and 8 lung adenocarcarcinomas without KRAS m...
ORGANISM(S): Homo sapiens 
2012-06-07 | E-GEOD-34914 | biostudies-arrayexpress
TranscriptomicsAn Integrated Model of the Transcriptome Landscape of HER2-Positive Breast Cancer
The goal of our study is to build an integrated transcriptome landscape model for HER2 positive breast tumors and identify the crucial signaling pathways associated with HER2 tumors. Genomic features include, 685 genes that were differentially expressed only in HER2-positive tumors, 102 genes that w...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-45419 | biostudies-arrayexpress
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