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UnknownFacilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels.
Not available
S-EPMC3003154 | biostudies-literature
UnknownIntravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production.
Not available
S-EPMC5349797 | biostudies-literature
TranscriptomicsCo-ordinate inhibition of autism candidate genes by topoisomerase inhibitors [Seq]
Topoisomerases are necessary for the expression of neurodevelopmental genes, and are mutated in some patients with autism spectrum disorder (ASD). We have studied the effects of inhibitors of Topoisomerase 1 (Top1) and Topoisomerase 2 (Top2) enzymes on mouse cortical neurons. We find that topoisomer...
ORGANISM(S): Mus musculus 
2013-08-30 | E-GEOD-43526 | biostudies-arrayexpress
TranscriptomicsChIP-chip from H9 hESCs for RNA Polymerase II, TBP, TAF3, TAF5, TAF7, and TAF11
The general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and approximately 14 TBP-associated factors (TAFs). Here we find, unexpectedly, that undifferentiated human embryonic stem cells (hESCs) contain only six TAFs (TAFs 2, 3, 5, 6, 7 and 11), whereas following diffe...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-39312 | biostudies-arrayexpress
UnknownSubstrate Specificity and Chemical Mechanism for the Reaction Catalyzed by Glutamine Kinase.
Not available
S-EPMC6643271 | biostudies-literature
TranscriptomicsWhole-genome in vitro expression analysis of F. tularensis isolates grown to mid log phase
This study was aimed to perform comparative expression analysis of both virulent and avirulent strains of F. tularensis with a goal to possibly identify genes unique to low and high virulent strains to understand their role, if any in virulence features of an isolate. Initially, thirty strains were ...
ORGANISM(S): Francisella tularensis 
2011-02-28 | E-GEOD-26048 | biostudies-arrayexpress
ProteomicsAvadomide induces degradation of ZMYM2 fusion oncoproteins in hematologic malignancies
Renneville A, Gasser JA, Grinshpun DE , Jean Beltran PM, Udeshi ND, Dr. Mary E. Matyskiela , Clayton T, McConkey M, Viswanathan K, Tepper A, Guirguis AA, Sellar RS, Cotteret S, Marzac C, Saada V, de Botton S, Kiladjian J, Cayuela J, Rolfe M, Chamberlain PP, Carr SA, Ebert BL. 2021. Thalidomide analo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-18 | MSV000086902 | MassIVE
ProteomicsProteomic profiling of archeological human bone
We performed shotgun proteomics of human remains using rib bones from the Hitotsubashi site (1657–1683 AD) in Tokyo, called Edo in ancient times. Two infants and six adults, including four elderly adults, were obtained from the skeletal collection of the Hitotsubashi site in Tokyo, Japan. The indiv...
ORGANISM(S): Homo sapiens (Human) 
2017-06-08 | PXD006256 | Pride
Bone Human Edo period Ancient proteins 
UnknownSecond Life and Classroom Environments: Comparing Small Group Teaching and Learning in Developing Clinical Reasoning Process Skills.
Not available
S-EPMC8368830 | biostudies-literature
TranscriptomicsGene profiling of the early healing rat medial collateral ligament
The objective of the study was to better understand the mechanism behind scar formation by identifying ECM factors and other unique genes differentially expressed during rat ligament healing via microarray. Rat medial collateral ligaments (MCL) were surgically transected or left intact. MCLs were co...
ORGANISM(S): Rattus norvegicus 
2013-06-06 | E-GEOD-47676 | biostudies-arrayexpress
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