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We identified a novel co-activator EAChm which enhances histone acetyation and transcription with acetytransferase chameau.
ORGANISM(S): Drosophila melanogaster 
2016-07-12 | GSE73098 | GEO
Chameau Activates Transcription with Enhancer of Acetyltransferase Chameau (EAChm) in vitro
Chameau (HBO1) regulates starvation in a temperature-dependent manner in Drosophila melanogaster
The fruit fly acetyltransferase chameau promotes starvation resilience at the expense of longevity
The coupling of metabolism to the posttranslational modification of proteins has been suggested to play an important role in the modulation of protein function in response to physiological variation. This interplay could potentially establish feedback loops that buffer extreme environmental challeng...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-09-05 | PXD035947 | Pride
The body temperature of Drosophila melanogaster depends on the extrinsic temperature. Numerous studies show that environmental temperature influences metabolism, lifespan, and starvation resilience. We have previously shown that Chameau (Chm), a MYST-domain acetyltransferase, promotes aging but also...
ORGANISM(S): Drosophila melanogaster 
2025-11-04 | GSE287187 | GEO
Proteins involved in cellular metabolism and molecular regulation can extend lifespan in various organisms in the laboratory. However, any improvement in aging would only provide an evolutionary benefit if the organisms were able to survive under non-ideal conditions. We have previously shown that D...
ORGANISM(S): Drosophila melanogaster 
2023-08-21 | GSE211042 | GEO
Proteins involved in cellular metabolism and molecular regulation have been shown to extend lifespan in various laboratory organisms. However, for any improvement in aging to confer an evolutionary benefit, organisms must also be able to survive under non-ideal conditions. Earlier, we discovered tha...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-09-05 | PXD042471 | Pride
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