Chang Lee C LC - OmicsDI

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Unknown (310)
Proteomics (28)
Transcriptomics (3)
Metabolomics (3)
Genomics (1)
Multiomics (1)

Organisms

Homo sapiens (15)
Mus musculus (13)
Akkermansia muciniphila ATCC BAA-835 (1)
Rattus norvegicus (1)
Saccharomyces cerevisiae (1)

Repository

pride (26)
biostudies-arrayexpress (4)
MetaboLights (3)
MassIVE (2)

Tissue

Cell culture (10)
Brain (3)
T cell (3)
Epithelial cell (2)
Heart (2)
Lymph node (2)
Permanent cell line cell (2)
Spleen (2)
Adipose tissue (1)
B cell (1)
Bone matrix (1)
Cardiocyte (1)
Cell suspension culture (1)
Colon (1)
Epithelium of pancreatic duct (1)
Fibroblast (1)
HEK-293 cell (1)
Kidney (1)
Liver (1)
Lung (1)
Macrophage (1)
Nerve cord (1)
Neuronal stem cell (1)
Pancreas (1)
Pancreatic stellate cell (1)
Primary cell (1)
Skin (1)
Testis (1)

Disease

Pancreatic ductal adenocarcinoma (2)
Brain cancer (1)
Breast cancer (1)
Cardiovascular system disease (1)
Colon cancer (1)
Parkinson's disease (1)

Technology Type

Mass Spectrometry (26)
Shotgun proteomics (13)
Bottom-up proteomics (5)
Gel-based experiment (5)
Data-dependent acquisition (4)
Mass spectrometry (3)
Affinity purification coupled with mass spectrometry proteomics (3)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
Immunopeptidomics (1)
Top-down proteomics (1)

Instrument Platform

LTQ Orbitrap Elite (1)
LTQ Orbitrap Velos (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS - positive - reverse phase (1)
MicrOTOF-Q II ESI-Qq-TOF (Bruker) (1)

Publication Date

2024 (6)
2026 (5)
2023 (4)
2022 (4)
2017 (3)
2025 (3)
2012 (2)
2021 (2)
2015 (2)
2013 (1)
2006 (1)
2019 (1)
2020 (1)

CHEBI ID

CHEBI:142273 (2)
CHEBI:165576 (2)
CHEBI:165591 (2)
CHEBI:173534 (2)
CHEBI:184421 (2)
CHEBI:26078 (2)
CHEBI:28619 (2)
CHEBI:30797 (2)
CHEBI:34900 (2)
CHEBI:35280 (2)
CHEBI:46961 (2)
CHEBI:5835 (2)
CHEBI:63866 (2)
CHEBI:67021 (2)
CHEBI:83053 (2)
CHEBI:87248 (2)
CHEBI:10049 (1)
CHEBI:10070 (1)
CHEBI:10093 (1)
CHEBI:101085 (1)
CHEBI:10120 (1)
CHEBI:10136 (1)
CHEBI:10782 (1)
CHEBI:109895 (1)
CHEBI:1109 (1)
CHEBI:111517 (1)
CHEBI:1157 (1)
CHEBI:116314 (1)
CHEBI:12387 (1)
CHEBI:124991 (1)

Metabolite Name

(1'S,2R,2'R,10'S,11'S,15'S)-17'-hydroxy-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane]-6',8'-diene-5,5'-dione (1)
(1-{1-[(4-hydroxy-3-methoxyphenyl)methyl]-7,8-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydro-2λ⁵-isoquinolin-2-yl}ethylidene)-λ⁴-oxidanyliumyl (1)
(10,14a-dihydroxy-2,2,4a,6a,6b,9,9,12a-octamethyl-docosahydropicen-13-yl)oxidanesulfonic acid (1)
(10S,14S)-10,14,20-trimethyl-16-methylidene-22-azahexacyclo[12.10.0.0²,¹¹.0⁵,¹⁰.0¹⁵,²³.0¹⁷,²²]tetracosan-5-ylium-7-olate (1)
(12aR)-4-(dimethylamino)-4a,5,10,12a-tetrahydroxy-6-methylidene-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aR)-7-chloro-4-(dimethylamino)-4,6,10,12a-tetrahydroxy-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aS)-4,7-bis(dimethylamino)-10,12,12a-trihydroxy-1,3,11-trioxo-9-(2-oxoacetamido)-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-2-carboximidic acid (1)
(12aS)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-5,10,12,12a-tetrahydroxy-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboximidic acid (1)
(13-{[5-(acetyloxy)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1,6,6,11,15-pentamethyl-14-(6-methylhept-5-en-2-yl)-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-9-yl)oxidanesulfonic acid (1)
(13R)-5-(3,4-dihydroxyphenyl)-6,9,17,19,21-pentahydroxy-13-(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.0²,¹¹.0³,⁸.0¹⁵,²⁰]henicosa-2(11),3(8),5,9,15,17,19-heptaen-7-one (1)
(15Z)-Octadec-15-en-9,11,13-triynoic acid (1)
(1R)-1,4-bis({[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-3-hydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1R,16Z,24E,26E,28Z)-1,18,26,27-tetrahydroxy-19,30-dimethoxy-12-[1-(3-methoxy-4-oxocyclohexyl)propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,16Z,24E,26E,28Z)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-19,30-dimethoxy-15,17,21,23,29-pentamethyl-35-methylidene-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,2R,3R,11S,12S,14R,26R)-5,6',7',12-tetrahydroxy-6-methoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1³,¹¹.0²,¹³.0⁴,⁹.0¹⁵,²³.0¹⁶,²⁰]triacontane-26,1'-isoquinoline]-4(9),5,7,15(23),16(20),21-hexaen-22-yl acetate (1)
(1R,2S,3R,4R,5S,6R,7S)-1,3,4,5,7,8,9,10,10-Nonachlorotricyclo[5.2.1.0²,⁶]dec-8-ene (1)
(1R,6S,12R,15S)-5,5-Dimethyl-11,13-dioxatetracyclo[7.5.1.0¹,⁶.0¹²,¹⁵]pentadec-8-ene (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-hydroxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-methoxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-13-(hydroxymethyl)-23,25-dimethoxy-19,21,27-trimethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1S)-1,3,4-trihydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1S,16Z,24E,26E,28Z)-1,18-dihydroxy-12-{1-[4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-15-(hydroxymethyl)-19,30-dimethoxy-17,21,23,29,35-pentamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1S,16Z,24E,26E,28Z)-1,18-dihydroxy-12-{1-[4-(2-hydroxyethoxy)-5-methoxy-2-oxocyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1S,2R,10S,11S,14R,15R)-2,15-Dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-ene (1)
(1S,2S,10S,11S,15R)-14-(5,6-dimethylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,17-diol (1)
(1S,2S,5R,7R,10S,11S,14R,15S,17S)-14-[(1R)-1,2-Dihydroxyethyl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14,17-triol (1)
(1S,2S,5S,10R,11S,14R,15R)-14-[(2R,5R)-5-Ethyl-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-ol (1)
(1S,2S,7S,10R,15R)-2,15-dimethyl-14-(1,4,6-trihydroxy-6-methylheptan-2-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,9,16-triol (1)
(1S,5R,13R,17S)-15-[(1S,3S,5R,13R)-10,14-Dimethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,14,16-pentaen-3-yl]-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,15-tetraen-14-one (1)
(2-Aminoethoxy)[(2R)-2-[(1Z,9Z)-octadeca-1,9-dien-1-yloxy]-3-[(6Z,9Z,12Z,15Z)-octadeca-6,9,12,15-tetraenoyloxy]propoxy]phosphinic acid (1)
(2-Aminoethoxy)[(2R)-2-[(5Z,8Z,11Z)-icosa-5,8,11-trienoyloxy]-3-[(9Z)-octadeca-1,9-dien-1-yloxy]propoxy]phosphinic acid (1)

Study type

Unknown experiment type (2)
DNA-seq (1)
Transcription profiling by array (1)

Release Date

2021 (51)
2022 (40)
2023 (39)
2024 (31)
2025 (30)
2020 (21)
2019 (19)
2018 (16)
2016 (15)
2015 (12)
2013 (9)
2011 (7)
2012 (6)
2017 (6)
2014 (6)
2026 (2)
2010 (2)
2006 (1)
2004 (1)

Lab affiliation

Department of Cell and Molecular Biology, College of Medicine, Chang Gung University, Taoyuan, Taiwan (2)
Roswell Park Cancer Center Buffalo, NY, USA (2)
Center for RNA Research, Institute for Basic Science, Seoul 08826, S. Korea School of Biological Sciences, Seoul National University, Seoul 08826, S. Korea (1)
Chair of Proteomics and Bioanalytics, Technical University of Munich (1)
Department of Chemistry, Korea University, Seoul 02841, Republic of Korea (1)
Department of Life Science, National Taiwan University (1)
Department of Pediatrics Medizinische Fakultät Carl Gustav Carus Technische Universität Dresden 01307 Dresden, Germany (1)
Department of Pharmacology, University of California, San Diego, La Jolla, CA 92037, USA. (1)
Department of Plant Biology, Carnegie Institution for Science, Stanford, California, USA (1)
Genomics Research Center, Academia Sinica (1)
Genomics Research Center, Academia Sinica, Taipei, Taiwan (1)
Genomics Research Center, Academia Sinica, Taipei, Taiwan. Drug Development Center, China Medical University, Taichung, Taiwan. Department of Biological Chemistry, University of California, Irvine. (1)
Group for Biometrology, Korea Research Institute of Standards and Science (KRISS), Daejeon, 34113, Republic of Korea (1)
Immune Synapse and Cell Therapy laboratory, Gwangju institute of science and technology (GIST), South Korea (1)
Institute for Basic Science and Seoul National University (1)
Korea Research Institute of Chemical Technology (1)
Lineberger Comprehensive Cancer Center Department of Pharmacology UNC Chapel Hill Chapel Hill NC USA (1)
Master program for clinical pharmacogehomics and pharmacoprotemics Chia-Li Han LAB.Taipei (1)
Northwestern University (1)
Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, 60611, USA Division of Hematology-Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA (1)
School of Biological Sciences, Seoul National University (1)
School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan (1)
Seoul National University (1)
Therapeutics & Biotechnology Division, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology (KRICT), (1)

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Endothelial Nitric Oxide Mediates the Anti-Atherosclerotic Action of Torenia concolor Lindley var. Formosama Yamazaki.

Not available

S-EPMC7073175 | biostudies-literature

Mouse (C57BL6/J) osteoblast LC-MS/MS

Physiological pathway of bone metabolism have been characterized well relatively. But antagonic pathway are less well studied. Here we investigated a negative regulator of osteogenesis with peroxiredoxin 5 (Prdx5) knockout mice that shows delay the bone metabolism. Prdx5-deficiency triggers a drasti...

ORGANISM(S): Mus musculus (Mouse)

2023-02-01 | PXD020082 | Pride

APOBEC3A is an Oral Cancer Prognostic Biomarker in Taiwanese Carriers of an APOBEC Deletion Polymorphism

Chen T-W, Lee C-C, Liu H, Wu C-S, Pickering CR, Huang P-J, et al., Nature Communications 8, Article number: 465 (2017) doi:10.1038/s41467-017-00493-9

Oral squamous cell carcinoma is a prominent cancer worldwide, p...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2019-08-28 | MSV000084250 | MassIVE

Comparative LC/MS-based profiling of L-arginine producing, canavanine resistant Corynebacterium glutamicum strain ATCC 21831 and type strain ATCC 13032

Corynebacterium glutamicum strain ATCC 21831 is a producer of L-arginine that was created by random mutagenesis. It is resistant to the arginine structural analogue canavanine. In order to identify potential bottlenecks in the biosynthetic pathway that leads to this industrially important amino acid...

2015-10-06 | MTBLS128 | MetaboLights

Metabolomic fingerprinting of bull spermatozoa for identification of fertility signature metabolites

The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...

2021-12-07 | MTBLS1071 | MetaboLights

Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired Acute Kidney Injury: A Retrospective Cohort Study.

Not available

S-EPMC4902543 | biostudies-literature

The DRD3 Ser9Gly Polymorphism Predicted Metabolic Change in Drug-Naive Patients With Bipolar II Disorder.

Not available

S-EPMC4998429 | biostudies-literature

Identification of proteins interacting with the small GTPase Arl4D by liposome flotation assay and mass spectrometry

N-terminal myristoylation serves as an important modification for membrane insertion and concrete membrane anchoring of the small GTPases ADP-ribosylation factor (Arf) and ADP ribosylation factor-like (Arl). To simulate the binding topology of Arl4D on the membrane, we performed the liposome flotati...

ORGANISM(S): Homo sapiens (Human)

2025-05-10 | PXD054952 | Pride

Erk2 Small gtpase arl4d Liposome flotation

Proteomics based analysis for associated PD-L1 in macrophage stimulated with extracellular adenosine signaling

We performed proteomics analysis to discover effector proteins for the post-transcriptional regulation of PD-L1 onhuman macrophages stimulated by adenosine signal.

ORGANISM(S): Mus musculus (Mouse)

2022-10-14 | PXD024512 | Pride

Macrophage adenosin

Trajectory of low-density lipoprotein cholesterol in patients with chronic kidney disease and its association with cardiovascular disease.

Not available

S-EPMC9360605 | biostudies-literature

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