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Transcriptomicsxyleme-Molecular bases of acclimation and adaptation to water deficit in poplar.
affy_popsec_orleans_poplar - xyleme - This project aims to identify candidate genes for water deficit acclimation and/or adaptation in a tree species: poplar. Due to compelling evidence that transcriptional regulation plays a major role in regulating many biological processes, we will look for genes...
ORGANISM(S): Populus x canadensis 
2012-12-15 | E-GEOD-17220 | biostudies-arrayexpress
ProteomicsEvaluation of depletion of abundant plasma proteins for proteomics characterization of EVs
In this study, we aimed to investigate if the removal of abundant plasma proteins prior to EV isolation could improve plasma-derived EV characterization by LC-MS/MS by improving the proteome coverage. Plasma depletion was performed using single-use spin columns prior to SEC-based EV isolation. After...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD039240 | Pride
Ev Plasma depletion Dia Extracellular vesicles Lc-ms/ms 
ProteomicsMorphine-treated Primary Brain Endothelial Cells LC-MS/MS DIA
This project aimed at investigating the impact of morphine exposure on brain endothelial cells via an in vitro monoculture of primary human brain microvascular endothelial cells (HBMECs) and state of the art mass spectrometry-based proteomics, using a data-independent acquisition (DIA) MS-based quan...
ORGANISM(S): Homo sapiens (Human) 
2022-03-21 | PXD024351 | Pride
Brain Dia Endothelial Morphine Lc-ms/ms 
Transcriptomicsrewatering-Global gene expression in young differentiating xylem of poplar in response to a drought –rewatering cycle
affy_rewatering_poplar - rewatering - Biological question (15 lines max): Xylogenesis is a complex process and is highly influenced by environmental factors. Numerous studies have shown xylem structural acclimation to moderate and long-lasting water deficits. A decrease in cell lumen size and an inc...
ORGANISM(S): Populus tremula x Populus alba 
2010-06-16 | E-GEOD-20061 | biostudies-arrayexpress
UnknownTumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
Not available
S-EPMC8029323 | biostudies-literature
TranscriptomicsHNF1-alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP1 & ChREBP activation
Biallelic inactivating mutations of the transcription factor 1 gene (TCF1), encoding hepatocyte nuclear factor 1a (HNF1a), were identified in 50% of hepatocellular adenomas (HCA) phenotypically characterized by a striking steatosis. To understand the molecular basis of this aberrant lipid storage, w...
ORGANISM(S): Homo sapiens 
2007-05-01 | E-GEOD-7473 | biostudies-arrayexpress
GenomicsEGAS00001002091 - samples
Using sequencing and gene expression analyses, we identified a subgroup of HCA characterized by fusion of the INHBE and GLI1 genes and activation of sonic hedgehog pathway. Molecular subtypes of HCAs associated with different patients’ risk factors for HCA, disease progression, and pathology feature...
EGAD00001003092 | EGA
GenomicsEGAS00001003685 - samples
Description not provided
EGAD00001005284 | EGA
GenomicsEGAS00001003686 - samples
Description not provided
EGAD00001005283 | EGA
GenomicsWhole Exome Sequencing of 15 Tumor/Normal pairs of inflammatory hepatocellular adenomas
The French ICGC project on liver tumors is coordinated by Pr Jessica Zucman-Rossi and funded by Inca (French Institute for Cancer). The aim of the present project is to identify the catalog of somatic and germline mutations in liver tumors. The present series corresponds to 15 Tumor/Normal pairs of ...
EGAS00001003686 | EGA
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