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Overall gene expression was evaluated in lnc CHASERR transfected human glioma T98G cells. The transcriptome of T98G cells transfected with sh-NC and sh-lnc CHASERR were compared.
Inducible fusion with the CHASERR long noncoding RNA transcript upregulates haploinsufficient CHD2 expression
We used high-throughput sequencing to analyse differentially expressed genes among human glioma cells T98G transfected with sh-lnc CHASERR.
ORGANISM(S): Homo sapiens 
2023-12-07 | GSE249202 | GEO
Long noncoding RNAs are now realized to function in various biological processes via multiple, and as of yet not fully understood, modes of action. CHASERR is a long noncoding RNA conserved throughout vertebrates, located immediately upstream of the promoter of the CHD2 gene. CHD2 haploinsufficiency...
ORGANISM(S): Homo sapiens Mus musculus 
2026-05-10 | GSE298095 | GEO
Here we focus on identifying conserved elements that are required for Chaserr function, a lncRNA that we recently characterized as being essential for mouse viability (https://doi.org/10.1038/s41467-019-13075-8). Chaserr is highly conserved in different species, and is located in close proximity (<2...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-18 | PXD023093 | Pride
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