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MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
ProteomicsUniversal and robust bacterial phosphoproteomics analysis
In present work, we established a simple and robust protocol for universal bacterial phosphoproteomic analysis underlying the rationale of methanol-based LLE protein extraction and cleanup. Using the SDS lysis as the conventional protocol control, we carefully evaluated the efficiency of protein ext...
ORGANISM(S): Escherichia Coli Cellular Organisms 
2025-08-04 | PXD055159 | JPOST Repository
MetabolomicsEffects of altering serine metabolic pathways and ROS levels on macrolide resistant strains of Streptococcus suis

In this study, we proposed to obtain the differential metabolic pathways before and after the development of macrolide resistance in Streptococcus suis strain ATCC700494 and the macrolide resistant strain obtained by pre-laboratory induction of strain ATCC700794 as the test strains by non-targete...

2022-07-12 | MTBLS4618 | MetaboLights
TranscriptomicsmicroRNA and mRNA expression profiles of human pancreatic islet-like cell clusters
Type 1 diabetes is an autoimmune destruction of pancreatic islet beta cell disease, and it is important to find new alternative source of the islet beta cells to replace the damaged cells. Human embryonic stem (hES) cells possess unlimited self-renewal and pluripotency and thus have the potential to...
ORGANISM(S): Homo sapiens 
2010-09-29 | E-GEOD-14503 | biostudies-arrayexpress
ProteomicsSNC1 phosphorylation sites invivo LC-MSMS
Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060129 | Pride
Lc-msms Snc1 
ProteomicsCPK3 phosphorylates SNC1-TIR LC-MSMS
Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060014 | Pride
Lc-msms Cpk3 Snc1-tir 
UnknownOverexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy.
Not available
S-EPMC6113252 | biostudies-literature
UnknownSurvival Benefit of Surgical Treatment for Elderly Patients with Intrahepatic Cholangiocarcinoma: A Retrospective Cohort Study in the SEER Database by Propensity Score Matching Analysis.
Not available
S-EPMC10047145 | biostudies-literature
TranscriptomicsRNA-seq analysis of flg22-induced gene expression changes in wild type, asr3-1 mutant and OX9 overexpression line
The correlation coefficient (R) for the expression profile of all transcripts between WT and asr3-1, and between WT and OX9 without flg22 treatment is close to linear, suggesting that ASR3 does not affect general gene transcription. Hierarchical clustering analysis flg22-induced genes in any of the ...
ORGANISM(S): Arabidopsis thaliana 
2015-08-26 | E-GEOD-63603 | biostudies-arrayexpress
UnknownMechanism of Liver Injury Induced by Cr6+ in Zebrafish and Protective Effect of Selenomethionine
Not available
S-EPMC12937444 | biostudies-literature
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