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UnknownDifferential requirement of TIR enzymatic activities in TIR-type immune receptor SNC1-mediated immunity
Not available
S-EPMC9706416 | biostudies-literature
ProteomicsCPK3 phosphorylates SNC1-TIR LC-MSMS
Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060014 | Pride
Lc-msms Cpk3 Snc1-tir 
TranscriptomicsA glycolytic enzyme enoalse negatively regulates plant immunity by repressing intracellular immune receptor NLR genes
AtLOS2 gene was isolated from a sensitized genetic screen aiming at the identification of negative regulators of SNC1 gene, a TIR-NLR gene. The whole genome transcriptome (RNA-seq) analysis of the los2-5 mutant revealed 1192 upregulated genes and 1140 downregulated genes in the mutant.
ORGANISM(S): Arabidopsis thaliana 
2022-02-05 | GSE156268 | GEO
UnknownMultiple functional self-association interfaces in plant TIR domains.
Not available
S-EPMC5347627 | biostudies-literature
UnknownCrystallization and preliminary X-ray diffraction analyses of the TIR domains of three TIR-NB-LRR proteins that are involved in disease resistance in Arabidopsis thaliana.
Not available
S-EPMC3818052 | biostudies-literature
ProteomicsSNC1 phosphorylation sites invivo LC-MSMS
Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060129 | Pride
Lc-msms Snc1 
UnknownThe Arabidopsis resistance-like gene SNC1 is activated by mutations in SRFR1 and contributes to resistance to the bacterial effector AvrRps4.
Not available
S-EPMC2973837 | biostudies-literature
UnknownSRFR1 negatively regulates plant NB-LRR resistance protein accumulation to prevent autoimmunity.
Not available
S-EPMC2940742 | biostudies-literature
GenomicsA glycolytic enzyme enoalse negatively regulates plant immunity by repressing intracellular immune receptor NLR genes
A glycolytic enzyme enoalse negatively regulates plant immunity by repressing intracellular immune receptor NLR genes
PRJNA657243 | ENA
UnknownIBR5 Modulates Temperature-Dependent, R Protein CHS3-Mediated Defense Responses in Arabidopsis.
Not available
S-EPMC4599859 | biostudies-literature
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