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Toll/interleukin-1 receptor (TIR) domain proteins are immune signaling components and function as NAD+-cleaving enzymes to activate defense responses. Activation of TIRs represses growth and drives cell death in plants and promotes axon degeneration in animals, but how plant TIRs are repressed remai...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-06-12 | PXD060129 | Pride
The disease resistance protein SNC1 represses the biogenesis of microRNAs and phased siRNAs [mRNA]
Plants evolved an array of disease resistance genes (R genes) to fight pathogens. In the absence of pathogen infection, NBS-LRR genes, which comprise a major subfamily of R genes, are suppressed by a small RNA cascade involving microRNAs (miRNAs) that trigger the biogenesis of phased siRNAs (phasiRN...
ORGANISM(S): Arabidopsis thaliana 
2018-10-09 | GSE111238 | GEO
Plants evolved an array of disease resistance genes (R genes) to fight pathogens. In the absence of pathogen infection, NBS-LRR genes, which comprise a major subfamily of R genes, are suppressed by a small RNA cascade involving microRNAs (miRNAs) that trigger the biogenesis of phased siRNAs (phasiRN...
ORGANISM(S): Arabidopsis thaliana 
2018-10-09 | GSE111239 | GEO
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